目的 分析ST段抬高型心肌梗死(ST-segment elevation myocardial infarction,STEMI)患者经皮冠状动脉介入术(percutaneous coronary intervention,PCI)后早期运动恐惧现状及其危险因素。方法 回顾性分析2022年1月—2025年1月于南京市第一医院行PCI治疗的150例STEMI患者临床资料,采用Tampa运动恐惧症量表(Tampa Scale for Kinesiophobia,TSK)评估患者早期运动恐惧现状,根据评分将患者分为恐动组(>37分,n=63)及非恐动组(≤37分,n=87),比较两组患者年龄、文化程度、经济状况、是否合并慢性疾病、术前左心室射血分数(left ventricular ejection fraction,LVEF)水平、婚姻状态、吸烟史、体质量指数(body mass index,BMI)、冠状动脉病变复杂程度(SYNTAX评分)、靶血管类型差异,统计两组一般自我效能感量表(General Self-Efficacy Scale,GSES)、社会支持评定量表(Social Support Rating Scale,SSRS)、广泛性焦虑障碍量表(Generalized Anxiety Disorder Scale,GAD)-2及主动寻求康复指导、对疾病的认知情况,采用单因素及多因素Logistic回归分析,采用Pearson相关系数评价恐动症Tampa评分表评分与GSES、SSRS、GAD-2评分的相关性。结果 STEMI患者PCI后早期恐动症发生率为42.00%;恐动组患者的年龄≥60岁占比、合并糖尿病占比、术前LVEF水平<40%占比、SYNTAX评分≥33分、GSES评分≤20分占比、SSRS评分≤30分占比、GAD-2评分≥3分占比均高于非恐动组。校正性别、文化程度、合并高血压、合并高脂血症、婚姻状态、吸烟史、BMI、主动询问康复计划、主动倾诉心理活动这些因素后,多因素分析显示,年龄、合并糖尿病、LVEF水平低、SYNTAX评分高、GSES评分低、SSRS评分低、GAD-2评分高均是影响STEMI患者PCI后早期运动恐惧的独立危险因素;Pearson相关分析显示,TSK评分与GAD-2评分呈正相关,与GSES、SSRS评分呈负相关。结论 STEMI术后早期运动恐惧的发生与患者年龄、合并糖尿病、术前LVEF水平、SYNTAX评分以及焦虑、自我效能感、社会支持密切相关。应重视对高危患者的识别和干预,通过提升患者的自我效能感和社会支持水平,降低其焦虑情绪,从而改善术后康复效果。
Abstract
Objective To analyze the status quo and risk factors of early kinesiophobia in patients with ST-segment elevation myocardial infarction (STEMI) after percutaneous coronary intervention (PCI). Methods The clinical data of 150 patients with STEMI who received PCI in Nanjing First Hospital from January 2022 to January 2025 were retrospectively analyzed. Tampa Scale for Kinesiophobia (TSK) was used to evaluate the status quo of early kinesiophobia. According to the score, the patients were divided into kinesiophobia group (>37 points, n=63) and non-kinesiophobia group (≤37 points, n=87). The differences in age, education level, presence or absence of chronic disease, preoperative left ventricular ejection fraction level, marital status, smoking history, body mass index (BMI), complexity of coronary artery disease (SYNTAX score) and target vessel type were compared between the two groups. The General Self-Efficacy Scale (GSES), Social Support Rating Scale (SSRS) and Generalized Anxiety Disorder Scale (GAD)-2, and actively seeking rehabilitation guidance, disease awareness were counted in both groups, and univariate and multivariate logistic regression analyses were adopted. Pearson correlation coefficient was used to assess the correlation between Tampa score and GSES, SSRS and GAD-2 scores. Results The incidence rate of early kinesiophobia in STEMI patients after PCI was 42.00%. The proportions of patients with age≥60 years old, concurrent diabetes mellitus, preoperative LVEF level<40%, SYNTAX score≥33 points, GSES score≤20 points, SSRS score ≤30 points and GAD-2 score≥3 points in kinesiophobia group were higher than those in non-kinesiophobia group. After adjusting for gender, education level, concurrent hypertension, concurrent hyperlipidemia, marital status, smoking history, BMI, active inquiry about rehabilitation plan, and active confiding of psychological activities, multivariate analysis showed that age, concurrent diabetes mellitus, low LVEF level, high SYNTAX score, low GSES score, low SSRS score and high GAD-2 score were independent risk factors of early kinesiophobia in STEMI patients after PCI. Pearson correlation analysis showed that TSK score was positively correlated with GAD-2 score, and negatively correlated with GSES score and SSRS score. Conclusion The occurrence of early kinesiophobia after STEMI is closely related to the age, concurrent diabetes mellitus, preoperative LVEF level, SYNTAX score, anxiety, self-efficacy and social support. It is necessary to pay attention to the identification and intervention of high-risk patients, and relieve the anxiety of patients by enhancing the self-efficacy and social support level, so as to improve the postoperative rehabilitation effect.
关键词
ST段抬高型心肌梗死 /
经皮冠状动脉介入术 /
早期 /
运动恐惧 /
自我效能感 /
社会支持 /
焦虑
Key words
ST segment elevation myocardial infarction /
percutaneous coronary intervention /
kinesiophobia /
self-efficacy /
social support /
anxiety
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参考文献
[1] 刘冉, 王宗方, 杨洋, 等. 冠状动脉内注射重组人尿激酶原治疗急性ST段抬高型心肌梗死的疗效[J]. 西北药学杂志, 2023, 38(4): 174-178.
[2] 马龙飞, 韩新宇, 陈昌, 等. STEMI患者外周血单个核细胞中MAPK通路与炎症反应及PCI后无复流的关系[J]. 分子诊断与治疗杂志, 2024, 16(3): 526-529.
[3] ZHAO H, MIAO R, LIN F, et al.Drug-Coated Balloon in Primary Percutaneous Coronary Intervention[J]. J Interv Cardiol, 2023, 2023: 5210808.
[4] TAN P, XIE X, GUO M, et al.Effects of rehabilitation management on lifestyle and quality of life of patients with coronary heart disease after percutaneous coronary intervention based on behavior change theory[J]. Minerva Surg, 2023, 78(3): 261-266.
[5] WOOD L, BEJARANO G, CSIERNIK B, et sal. Pain catastrophising and kinesiophobia mediate pain and physical function improvements with Pilates exercise in chronic low back pain: a mediation analysis of a randomised controlled trial[J]. J Physiother, 2023, 69(3): 168-174.
[6] DUPUIS F, CHERIF A, BATCHO C, et al.The Tampa Scale of Kinesiophobia: A Systematic Review of Its Psychometric Properties in People With Musculoskeletal Pain[J]. Clin J Pain, 2023, 39(5): 236-247.
[7] 任鹏娜, 张月, 丁琳, 等. 运动恐惧在急性心肌梗死经皮冠状动脉介入治疗术后患者自我效能与运动依从性间的中介效应[J]. 解放军护理杂志, 2022, 39(1): 21-24.
[8] HELLERYD E, RAWSHANI A, RAWSHANI A, et al.Association between exercise load, resting heart rate, and maximum heart rate and risk of future ST-segment elevation myocardial infarction (STEMI)[J]. Open Heart, 2023, 10(2): e002307.
[9] SHAJRAWI A, KHALIL H, AL-SUTRY M, et al.Exercise Self-efficacy, Perceived Benefits, and Barriers to Exercise Among Patients Following Acute Myocardial Infarction[J]. J Cardiovasc Nurs, 2021, 36(4): E11-E19.
[10] 江苏省医学会心血管病学分会, 江苏省医师协会心血管内科医师分会, 江苏省医师协会心脏重症专业委员会, 等. 急性ST段抬高型心肌梗死溶栓治疗专家共识[J]. 中国介入心脏病学杂志, 2024, 32(7): 364-382.
[11] 喻茂文, 覃左丽, 汤洪波, 等. 基于RAAS与Syntax评分构建冠心病合并高血压患者PCI治疗近期预后的Nomogram预测模型[J]. 国际检验医学杂志, 2025, 46(6): 719-727.
[12] 胡文. 简体中文版TSK和FABQ量表的文化调适及其在退行性腰腿痛中的应用研究[D]. 上海: 第二军医大学, 2012.
[13] 王才康, 胡中锋, 刘勇. 一般自我效能感量表的信度和效度研究[J]. 应用心理学, 2001, 7(1): 37-40.
[14] 肖水源. 《社会支持评定量表》的理论基础与研究应用[J]. 临床精神医学杂志, 1994, (2): 98-100.
[15] 谢婷, 袁源, 雍桂珍, 等 GAD-2评估功能性消化不良患者伴焦虑状态的应用研究[J]. 胃肠病学和肝病学杂志, 2021, 30(6): 643-647.
[16] 张亚楠, 李利侠, 李红影, 等. 非ST段抬高心肌梗死PCI治疗后患者疾病感知对遵医行为的影响[J]. 湖南师范大学学报 (医学版), 2022, 19(1): 275-278.
[17] 许亚平, 吴静, 唐晓磊. 白细胞/平均血小板体积比值 (WMR), 纤维蛋白原/白蛋白比值 (FAR) 在预测急性ST段抬高型心肌梗死预后临床价值[J]. 湖南师范大学学报: 医学版, 2022, 19(1): 5.
[18] LI Q, YAN L, XING W, et al.The effect of fear-avoidance intervention on kinesiophobia and self-efficacy in patients after percutaneous coronary intervention: study protocol for a clinical randomized controlled trial[J]. Trials, 2024, 25(1): 517.
[19] ZHU Y, WANG Z, SU T, et al.Kinesophobia and its related factors in patients after percutaneous coronary intervention: A cross-sectional study[J]. J Clin Nurs, 2024, 33(12): 4692-4707.
[20] 张程, 王霄一, 杨文娟, 等. 双向社会支持在老年维持性血液透析患者中的应用研究[J]. 中华护理杂志, 2025, 60(07): 813-819.
[21] 张田岳, 李爱丽, 朱碧云, 等. 二元应对在脑卒中后运动障碍患者配偶领悟社会支持和家庭关系间的中介效应[J]. 中华行为医学与脑科学杂志, 2025, 34(02): 158-163.
基金
江苏省医学会介入医学第三期科研专项资金项目“滤器直径与滤器源性下腔静脉内膜增生相关性实验研究”[SYH-3201140-0088(2023035)]