目的: 分析比较FOLEY导管与地诺前列酮栓促宫颈成熟的疗效及安全性。方法: 选取2024年1月—2024年12月我院收治的待产孕妇100例为研究对象,随机将患者分为对照组和观察组,每组各50例。对照组患者给予地诺前列酮栓促宫颈成熟治疗,观察组患者给予FOLEY导管促宫颈成熟治疗,分析比较FOLEY导管与地诺前列酮栓促宫颈成熟的疗效及安全性。结果: 对照组宫颈成熟度与观察组无显著性差异,均具有理想的促宫颈成熟效果;与对照组比较,观察组待产孕妇剖宫产比例无明显增加,且新生儿Apgar评分、新生儿体重均无显著差异,但观察组产后出血量减少;观察组不良妊娠结局中胎儿窘迫,新生儿窒息,胎膜早破较对照组均有减少,但两者无显著差异;而子宫过度刺激、羊水污染、胎心异常、宫缩过频情况观察组均显著低于对照组。结论: FOLEY导管促宫颈成熟与地诺前列酮栓效果相当,但更加安全可靠。
Abstract
Objective To analyze and to compare the efficacy and safety of FOLEY catheter and Dinoprostone suppository in promoting cervical ripening. Methods A total of 100 pregnant women admitted to our hospital from January 2024 to December 2024 were selected as the research subjects. They were randomly divided into a control group and an observation group, with 50 cases in each group. The control group was treated with Dinoprostone to promote cervical ripening, while the observation group received FOLEY catheter for the same purpose. The efficacy and safety of the two methods were analyzed and compared. Results There was no significant difference in cervical ripening between the control group and the observation group, all have ideal cervical ripening effects. Compared with the control group, the observation group showed no significant increase in the cesarean section rate, and there were no significant differences in neonatal Apgar scores or neonatal weight. Although the observation group had reductions in postpartum hemorrhage, adverse pregnancy outcomes such as fetal distress, neonatal asphyxia, and premature rupture of membranes, these differences were not statistically significant. However, the incidences of uterine hyperstimulation, meconium-stained amniotic fluid, abnormal fetal heart rate, and frequent uterine contractions in the observation group were significantly lower than those in the control group.
关键词
FOLEY导管 /
地诺前列酮栓 /
促宫颈成熟
Key words
FOLEY catheter /
dinoprostone suppository /
cervical ripening
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基金
长沙市自然科学基金“肌醇干预改善妊娠期糖尿病患者血糖的随机对照研究及相关机制探讨”（kq2202471）
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