目的:探讨住院共病老年患者衰弱与营养状况之间的相关性。方法:收集湖南省某三甲医院住院的共病老年患者200例,根据FARIL衰弱评估量表将住院共病老年患者分为无衰弱组、衰弱前期组、明显衰弱组。采用微型营养评估量表评估住院共病老年患者的营养状态,统计分析住院共病老年患者衰弱与营养状况之间的相关性。结果:FARIL衰弱得分与文化程度、家庭人均月收入呈显著负相关,而与年龄、共病指数、营养风险呈显著正相关。营养指标如PA、TP、ALB、Hb、25羟维生素D、IgA、IgG、IgM、补体C3、补体C4与衰弱得分呈显著负相关。住院共病老年患者的衰弱与营养风险之间存在显著的相关性(OR=1.047,95%CI:1.241~4.914,P<0.01)。结论:住院共病老年患者的营养不良与衰弱程度密切相关。
Abstract
Objective To explore the current situation and correlation between frailty and nutritional status of hospitalized comorbidities in elderly patients. Methods A total of 200 hospitalized elderly patients with comorbidities participated in the survey. According to the FARIL frailty assessment scale, hospitalized elderly patients with comorbidities were divided into non frailty group, pre frailty group, and obvious frailty group. Nutritional risk screening was used to evaluate the nutritional status of hospitalized elderly patients with comorbidities, and the correlation between frailty and nutritional status was statistically analyzed. Results There were frailty score is significantly negatively correlated with educational level and per capita monthly income of households, but significantly positively correlated with age, comorbidity index, and nutritional risk. Nutritional indicators such as PA, TP, ALB, Hb, 25 hydroxyvitamin D, IgA, IgG, IgM, complement C3, complement C4 are significantly negatively correlated with frailty scores. Of particular note, there is the most significant correlation between frailty and nutritional risk in hospitalized comorbid elderly patients (OR=1.047, 95%CI: 1.241-4.914, P<0.01). Conclusion The treatment Malnutrition and frailty in hospitalized comorbid elderly patients are closely related, and personalized nutritional intervention strategies can improve nutritional status and reduce the risk of frailty.
关键词
老年 /
衰弱 /
营养状况
Key words
elderly /
weakness /
nutritional status
{{custom_sec.title}}
{{custom_sec.title}}
{{custom_sec.content}}
参考文献
[1] 刘倩倩, 安稳, 杜娜, 等. 医养结合机构高龄住院共病老年患者衰弱状态分布及其影响因素[J]. 吉林大学学报 (医学版), 2023, 49(1): 173-179.
[2] 吴兰心, 张艳, 孟李雪, 等. 老年共病患者自我管理现状及影响因素分析[J]. 中国全科医学, 2024, 27(21): 2565-2566.
[3] 陈木欣, 梁好, 赵怡迪, 等. 不同衰弱评估工具在老年术前衰弱筛查中的应用效果比较研究[J]. 中国全科医学, 2024, 27(30): 3790-3796.
[4] 衡艳林, 齐桂, 刘非凡. 老年衰弱综合征发生情况及其相关因素[J]. 中国老年学杂志, 2023, 43(09): 2270-2273.
[5] SINGH M, JENSEN MD, LERMAN A, et al.Effect of Low-Dose Rapamycin on Senescence Markers and Physical Functioning in Older Adults with Coronary Artery Disease: Results of a Pilot Study[J]. J Frailty Aging, 2016, 5(4): 204-207.
[6] 韩雨, 杨洋, 叶向红, 等. 老年恶性肿瘤病人衰弱与肌少症关系的研究进展 [J]. 肠外与肠内营养, 2022, 29(04): 248-251+256.
[7] RUBENSTEIN LZ, HARKER JO, SALVÀ A, et al.Screening for undernutrition in geriatric practice: developing the short-form mini-nutritional assessment (MNA-SF)[J]. J Gerontol A Biol Sci Med Sci, 2001, 56(6): M366-372.
[8] AL-SARAYFI D, BRINK M, CHAMULEAU MED, et al.R-miniCHOP versus R-CHOP in elderly patients with diffuse large B-cell lymphoma: A propensity matched population-based study[J]. Am J Hematol, 2024, 99(2): 216-222.
[9] WANG Q, WANG J, DAI G .Prevalence, characteristics, and impact on health outcomes of frailty in elderly outpatients with diabetes: A cross-sectional study[J]. Medicine, 2023, 102(47): e36187.
[10] PHILIPP L, MARKUS M, ANNE A, et al.The Role of Age and Comorbidities in Esophagogastric Cancer Chemoradiation of the Frail Elderly (>70 Years): An Analysis from a Tertiary High Volume-Center[J]. Cancers, 2022, 15(1): 106.
[11] FUSCHI A, ASIMAKOPOULOS AD, SCALZO S, et al.B-TURP versus HoLEP: Peri-Operative Outcomes and Complications in Frail Elderly (>75 y.o.) Patients: A Prospective Randomized Study[J]. Biomedicines, 2022, 10(12): 3212.
[12] RASHIDI M, YILDIRIM G, KARAMAN F, et al.Determination of the relationship between frailty level and quality of life in elderly individuals with type 2 diabetes[J]. Sci Rep, 2024, 14(1): 32028.
[13] MARIONA F E, JOAN P E, ROSA B N, et al.Assessment of frailty in elderly patients attending a multidisciplinary wound care centre: a cohort study[J]. BMC Geriatrics, 2021, 21(1): 727.
[14] BLAUTH FG, VILAR LADS, PONTES VCB, et al.The effect of frailty on the 24-hour blood pressure pattern in the very elderly.[J]. Journal of clinical hypertension (Greenwich, Conn. ), 2021, 24(1): 67-73.
基金
湖南省保健专项资金科研课题“住院共病老年患者衰弱与营养状况相关性研究”(B2022-03)