目的：研究脑动脉瘤神经介入术后神经系统并发症风险的危险因素。方法：纳入2018年1月―2021年3月于我院收治的14例接受神经介入手术治疗后发生神经系统并发症的囊性未破裂脑动脉瘤患者为神经系统并发症组,另选取同期入院行神经介入手术治疗但未发生神经系统并发症的121例囊性未破裂脑动脉瘤患者为非神经系统并发症组。统计两组患者一般资料,使用多因素Logistic回归分析评价患者神经介入术后神经系统并发症的独立危险因素。结果：既往短暂性脑缺血发作或脑梗死病史（OR=3.505,95%CI：1.852~6.633）、心血管合并症（OR=3.7294,95%CI：1.527~7.106）、动脉瘤最大直径（OR=3.572,95%CI：1.870~6.823）、宽颈动脉瘤（OR=2.883,95%CI：1.510~5.504）、不规则形态或存在子囊（OR=2.194,95%CI：1.140~4.222）是脑动脉瘤患者神经介入术后神经系统并发症的独立危险因素（P<0.05）。结论：脑动脉瘤患者神经介入术后神经系统并发症的危险因素众多,包括既往短暂性脑缺血发作或脑梗死病史、心血管合并症、动脉瘤最大直径>10mm、宽颈动脉瘤、动脉瘤不规则形态或存在子囊有关,临床上应引起足够重视。
Abstract
Objective To study the risk factors of neurological complications after Neurointerventional interventional neurosurgery for Intracranial aneurysm. Methods Fourteen patients with unruptured cystic Intracranial aneurysms who had neurological complications after undergoing neurointerventional surgery in our hospital from January 2018 to March 2021 were included as the neurological complications group, and 121 patients with unruptured cystic Intracranial aneurysm who had received neurointerventional surgery at the same time but had no neurological complications were selected as the non neurological complications group. Collect general data from two groups of patients and use multivariate logistic regression analysis to evaluate the independent risk factors for neurological complications after neurological intervention surgery in patients. Results Previous history of transient ischemic attack or cerebral infarction (OR=3.505, 95%CI=1.852~6.633), cardiovascular complications (OR=3.294, 95%CI=1.527~7.106), maximum diameter of aneurysms (OR=3.572, 95%CI=1.870~6.823), wide-necked aneurysms (OR=2.883, 95%CI=1.510~5.504), and no aneurysms. Regular shape or presence of ASCUS (OR=2.194, 95%CI=1.140~4.222) were independent risk factor for neurological complications in patients with Intracraniall aneurysm after neurointervention (P<0.05). Conclusion There are many risk factors for neurological complications in patients with Intracranial aneurysms after neurointerventional, including previous transient ischemic attack or cerebral infarction history, cardiovascular complications, aneurysms with a maximum diameter of>10mm, wide-necked aneurysms, irregular shape of the aneurysm or the presence of sacs, which should be paid enough attention in clinical practice.
关键词
脑动脉瘤 /
神经介入手术 /
神经系统并发症
Key words
intracranial aneurysm /
neurointerventional surgery /
neurological complications
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