Effects of Yixuesheng capsule combined with iron supplement on iron metabolism indexes, red blood cell-related indexes and maternal-infant outcomes of iron-deficiency anemia during pregnancy
LI Limin, TANG Shifu, LI Yehua, LIU Xin, ZHENG Jinjian, ZHANG Lanzuo
Department of Clinical Laboratory, Liuzhou People's Hospital, Liuzhou 545006, China
Abstract：Objective To explore the effects of Yixuesheng capsule combined with iron supplement in the treatment of iron deficiency anemia during pregnancy on iron metabolism indexes, red blood cell-related indexes and maternal-infant outcomes. Methods 300 patients with iron deficiency anemia during pregnancy from April 2020 to April 2022 were divided into three groups (iron supplement group, Yixuesheng capsule group and combined group) by the random number table method. The iron supplement group was given iron supplement treatment, and the Yixuesheng capsule was treated with Yixuesheng capsule, and the combined group was given iron supplement combined with Yixuesheng capsule. All patients and neonates were followed up until 3 months after the end of pregnancy. The therapeutic efficacy, neonatal growth and development as well as iron metabolism indexes and red blood cell indexes before and after treatment were compared among the three groups. Results The total effective rate of treatment in combined group was higher than that in iron supplement group and Yixuesheng capsule group. Serum ferritin, iron level and ferritin saturation after treatment in combined group were higher than those in iron supplement group and Yixuesheng capsule group, and the above indexes in iron supplement group were higher than those in Yixuesheng capsule group. The hemoglobin, mean corpuscular volume, mean corpuscular hemoglobin and mean corpuscular hemoglobin concentration after treatment were higher in combined group than those in iron supplement group and Yixuesheng capsule group. The birth weight at birth was heavier in combined group than that in iron supplement group and Yixuesheng capsule group. The incidence rate of adverse maternal-infant pregnancy outcomes in combined group was lower compared with that in iron supplement group and Yixuesheng capsule group (4.00% vs 14.00%, 12.00%). Conclusion Yixuesheng capsule combined with iron supplement has high effective rate in the treatment of iron deficiency anemia during pregnancy, and it can improve the iron metabolism and red blood cell function, relieve the degree of anemia, promote the fetal growth and development, and lower the adverse pregnancy outcomes.
李丽敏, 唐石伏, 李烨华, 刘欣, 郑金坚, 张兰作. 益血生联合铁剂治疗妊娠期缺铁性贫血对铁代谢指标、红细胞相关指标及母婴结局的影响[J]. 湖南师范大学学报(医学版), 2023, 20(3): 102-106.
LI Limin, TANG Shifu, LI Yehua, LIU Xin, ZHENG Jinjian, ZHANG Lanzuo. Effects of Yixuesheng capsule combined with iron supplement on iron metabolism indexes, red blood cell-related indexes and maternal-infant outcomes of iron-deficiency anemia during pregnancy. HuNan ShiFan DaXue XueBao(YiXueBan), 2023, 20(3): 102-106.
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2023, Vol. 20 
