Objective To explore the clinical effect of Qidongyixin Granule combined with auricular point sticking in the treatment of elderly cardiac neurosis. Methods A total of 80 elderly patients with cardiac neurosis were recruited at our hospital between July 2024 and July 2025. Participants were randomly assigned to either the auricular point group (n=40) or the combined group (n=40) using the random number method. The auricular point group received auricular point sticking treatment, while the combined group underwent treatment with Qidong Yixin granules in conjunction with auricular point sticking therapy. The Hamilton Depression Scale (HAMD) score, Hamilton Anxiety Scale (HAMA) score, Traditional Chinese Medicine (TCM) syndrome quantification score, clinical efficacy, routine electrocardiogram, and liver and kidney function safety were assessed for both groups prior to treatment and at 1 and 2 months post-treatment. Results The total effective rate in the combined group was significantly higher than that in the auricular point group (P<0.05). Compared with pre-treatment levels, the HAMD and HAMA scores of elderly patients in both groups decreased at the 1st and 2nd months post-treatment (P<0.05), with the combined group showing lower scores than the auricular point group (P<0.05). Similarly, compared with pre-treatment levels, the scores for TCM syndromes such as palpitation, chest tightness or pain, depression, shortness of breath, fatigue, insomnia, and the total score all decreased after treatment in both groups (P<0.05), and the scores in the combined group were lower than those in the auricular point group (P<0.05). The total effective rate of electrocardiogram improvement in the combined group was significantly higher than that in the auricular point group after treatment (P<0.05). No significant differences were observed in creatine kinase (CK), aspartate aminotransferase (AST) and alanine aminotransferase (ALT) levels between the two groups before and after treatment (P>0.05). Compared with before treatment, the levels of creatine kinase isoenzyme (CK-MB), serum creatinine (Scr), and blood urea nitrogen (BUN) in both groups were decreased (P<0.05) after treatment, and the decreases in Scr and BOW levels were more significant in the combination group (P<0.05). Conclusion Qidongyixin Granule combined with auricular point sticking has better clinical efficacy in the treatment of elderly cardiac neurosis, which can reduce HAMD and HAMA scores, TCM syndrome scores, liver and kidney function related indexes of elderly patients, increase the total effective rate of electrocardiogram, improve the overall treatment effect, and provide a more optimized plan for clinical use, which is worth promoting.
Key words
cardiac neurosis /
Qidongyixin granules /
auricular point sticking /
Hamilton depression rating scale /
Hamilton anxiety scale
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