Effect of Multidisciplinary Standardized Evidence-Based Intervention on Patients with Cerebral Contusion and Laceration Complicated by Pneumonia

LI Wuxia; GAO Liang

PDF(2007 KB)

Journal of Hunan Normal University(Medical Science) ›› 2026, Vol. 23 ›› Issue (3) : 52-57.

Effect of Multidisciplinary Standardized Evidence-Based Intervention on Patients with Cerebral Contusion and Laceration Complicated by Pneumonia

LI Wuxia, GAO Liang

Author information +

History +

Abstract

Objective To explore the effect of multidisciplinary standardized evidence-based intervention on patients with brain contusion and laceration complicated by pneumonia. Methods From August 2023 to August 2024, 110 patients with brain contusion complicated by pneumonia and laceration hospitalized in the neurosurgery department of a tertiary grade A hospital were enrolled in this study. They were divided into a control group and an observation group according to random number table method. Patients in the control group received routine intervention measures, while those in the observation group received multidisciplinary standardized evidence-based intervention. The two groups were compared in terms of lung function[forced expiratory volume in one second (FEV₁) and forced vital capacity (FVC) ], the 36-Item Short Form Health Survey (SF-36) scores, Mini-Mental State Examination (MMSE) scores, Prognostic Nutritional Index (PNI) scores and Clinical Pulmonary Infection Score (CPIS) before and after intervention, duration of mechanical ventilation, length of ICU stay, and incidence of adverse events during intervention. The duration of mechanical ventilation and length of ICU stay were taken as primary study endpoints. Results After intervention, the observation group showed higher FEV1, FVC, and FEV1/FVC ratio than the control group (P<0.05). After intervention, scores for all domains of the SF-36 in the observation group were higher than those in the control group (P<0.05). After intervention, the observation group had higher MMSE and PNI scores, and lower CPIS scores than the control group (P<0.05). The duration of mechanical ventilation and length of ICU stay were shorter in the observation group than in the control group (P<0.05). No statistically significant difference was found in adverse events between the two groups during intervention (P>0.05). Conclusion Multidisciplinary standardized evidence-based intervention can effectively improve lung function, cognitive function, and nutritional status in patients with cerebral contusion and laceration complicated by pneumonia. It also can reduce the severity of pulmonary infection, enhance quality of life, and shorten the duration of mechanical ventilation and ICU stay. It is worthy of clinical application.

Key words

multidisciplinary standardized evidence-based intervention / brain contusion and laceration / pneumonia / lung function / prognosis

Cite this article

EndNote

Ris (Procite)

Bibtex

Download Citations

LI Wuxia, GAO Liang. Effect of Multidisciplinary Standardized Evidence-Based Intervention on Patients with Cerebral Contusion and Laceration Complicated by Pneumonia[J]. Journal of Hunan Normal University(Medical Science). 2026, 23(3): 52-57

References

[1] 王志星, 王卫, 舒道坤. 醒脑静对脑挫裂伤患者神经功能及炎性因子水平的影响[J]. 中华神经外科疾病研究杂志, 2024, 18(6): 51-54.
[2] SARKAR H.Risk factors for postoperative brain contusion and early outcomes in patients with anterior skull base meningiomas undergoing unifrontal surgery: single center experience with 110 patients[J]. Neurol India, 2023, 71(5): 1027-1028.
[3] 苏晓丽. 快速康复外科护理在脑挫裂伤患者中的应用效果[J]. 中国乡村医药, 2023, 30(6): 26-27.
[4] XIE Q, LI Q, FANG H, et al.Gut-derived short-chain fatty acids and macrophage modulation: exploring therapeutic potentials in pulmonary fungal infections[J]. Clin Rev Allergy Immunol, 2024, 66(3): 316-327.
[5] 陈焦焦, 王春霞, 谢海花. 针对性护理对脑挫裂伤患者认知功能, 神经功能及生活自理能力的影响观察[J].贵州医药, 2025, 49(10): 1674-1675.
[6] 李小珍, 傅桂芬, 朱新青, 等. 中年肥胖糖尿病前期人群营养干预的循证医学证据总结[J]. 中华临床营养杂志, 2025, 33(06): 436-443.
[7] 贺应军, 章士刚, 方蓉, 等. 基于JBI循证医学模式的老年胃癌术后患者肠内营养缺乏预防护理干预方案研究及评价[J]. 现代中西医结合杂志, 2021, 30(23): 2596-2600, 2604.
[8] 李大苇, 李道昌, 沈丽, 等. 基于循证的集束化预防干预对颅脑损伤肠内营养患者并发腹泻的影响[J]. 中国实用护理杂志, 2025, 41(07): 481-486.
[9] 白云艳, 陈晗, 鞠二琳. 基于循证理论的个体化综合干预对冠心病PCI患者负性情绪, 心脏康复认知及并发症的影响[J]. 中国全科医学, 2023, 26(S01): 73-75.
[10] 崔玉红, 张培, 卢艺.基于全视角风险预控及循证理论的护理干预对心脏瓣膜置换术患者术后谵妄及并发症的效果评价[J]. 现代医学, 2025, 53(3): 438-443.
[11] ZHANG Y, WU X, LU M, et al.Effectiveness of bundled care in the management of cerebral hemorrhage complicated by pulmonary infection in China: A systematic review and meta-analysis[J]. PLoS one, 2024, 19(11): e0312882.
[12] 刘宁, 薛娜, 孔令常, 等. 老年颅脑损伤患者术后肺部感染危险因素分析及对策[J]. 齐鲁护理杂志, 2024, 30(10): 132-135.
[13] 池千勉, 黎华文, 郑碧莹. 强化呼吸道护理对ICU肺癌患者排痰效果及肺部感染的影响[J]. 中外医疗, 2024, 43(14): 170-173.
[14] 张红梅, 陈淑萍, 王博, 等. 基于老年综合评估的人文关怀对老年肺部感染患者心理韧性及满意度的影响[J]. 国际护理学杂志, 2024, 43(8): 1456-1460.
[15] 曹勇, 郑慧军, 苑亚东, 等. 高血压脑出血患者术后早期气管切开对肺部感染的预防[J]. 中华医院感染学杂志, 2016, 26(8): 1750-1752.
[16] 莫曼龙, 刘端绘, 梁振杰, 等. 动态调控气囊压力与声门下吸引联合应用于预防呼吸机相关性肺炎的价值分析[J]. 临床和实验医学杂志, 2018, 17(8): 841-844.
[17] 张威, 谢模政, 施于, 等. 持续人工气道应用动态气囊压力调控联合声门吸引对VAP预防效果及病死率的影响[J]. 河北医药, 2022, 44(13): 2000-2002, 2006.
[18] 霍佳佳, 方萍, 王玲, 等. 医疗失效模式与效应分析管理模式在降低急性脑卒中患者肺部感染中的应用研究[J]. 护士进修杂志, 2024, 39(6): 647-652+658.
[19] 李鲁, 王红妹, 沈毅. SF-36健康调查量表中文版的研制及其性能测试[J]. 中华预防医学杂志, 2002, 36(2): 109-113.
[20] 李格, 沈漁邨, 陈昌惠, 等. 老年痴呆简易测试方法研究——MMSE 在城市老年居民中的测试[J]. 中国心理卫生杂志, 1988, 2(1): 13-18.
[21] 许文娟, 马莹, 王译民, 等. 预后营养指数预测小细胞肺癌预后的临床应用研究[J]. 四川大学学报 (医学版), 2020, 51(4): 573-577.
[22] 王一律, 王真, 钟文, 等. PCT和hs-CRP联合临床肺部感染评分对老年重症肺炎患者预后评估的价值[J]. 河北医学, 2023, 29(2): 289-293.
[23] 余娟, 胡颖. 基于归因分析的预见性干预在预防脑出血开颅术后深静脉血栓肺部感染中的应用价值[J]. 基层医学论坛, 2024, 28(8): 85-87.
[24] 赵斌, 杨琦. 个性化康复护理在脑卒中合并肺部感染患者中的应用效果观察[C]//榆林市医学会. 第四届全国医药研究论坛论文集(上). 西安, 榆林市医学会, 2024: 497-502.
[25] 杨萍, 张聪. 基于损伤控制理论的护理干预对重症颅脑损伤脑积水患者神经功能恢复和生命质量的影响[J]. 罕少疾病杂志, 2024, 31(8): 20-22, 28.
[26] 蔡欣欣, 汤鹤年, 张冬英. 循证护理对肺癌术后免疫治疗患者的影响分析[J]. 心理月刊, 2022, 17(8): 91-93.