Objective To analyze the predictive value of electrocardiogram parameters combined with serum N-terminal pro-brain natriuretic peptide (NT-proBNP) on major adverse cardiac events (MACE) in elderly patients with acute myocardial infarction (AMI). Methods 104 elderly patients with AMI in the hospital were retrospectively selected from June 2021 to February 2024, and they received electrocardiogram examination. Serum NT-proBNP level was detected. The above patients were divided into MACE group (n=46) and non-MACE group (n=58) according to whether MACE occurred within 6 months after discharge. The predictive value of electrocardiogram parameters[QT/QTc interval, P wave dispersion (Pd), QRS wave duration]combined with serum NT-proBNP on MACE occurrence in elderly patients with AMI was analyzed. Results QT interval, QTc interval, Pd, QRS wave duration, NT-proBNP, left ventricular end-systolic diameter (LVESD) and left ventricular end-diastolic diameter (LVEDD) in MACE group were higher than those in non-MACE group, while left ventricular ejection fraction (LVEF) was lower than that in non-MACE group. Pearson correlation analysis suggested that QT interval, QTc interval, Pd and QRS wave duration were positively correlated with LVESD and LVEDD, and those indicators were negatively correlated with LVEF. Binary logistic regression analysis showed that QT interval, QTc interval, Pd, QRS wave duration, NT-proBNP, LVESD, LVEDD and LVEF were independent influencing factors of the prognosis of elderly patients with AMI. ROC curve indicated that the areas under the ROC curves of QT interval, QTc interval, Pd, QRS wave duration, NT-proBNP and combined detection for predicting the prognosis of elderly patients with AMI were 0.875, 0.753, 0.842, 0.894, 0.840 and 0.985, and combined prediction had high efficiency. Conclusion Electrocardiographic parameters,including the QT/QTc interval,P-wave dispersion（Pd）,and QRS duration,along with serum NT-proBNP levels,are closely associated with cardiac function in elderly patients with acute myocardial infarction（AMI）. Their combined assessment demonstrates good predictive efficacy for the prognosis of these patients,offering high clinical reference value.
Key words
acute myocardial infarction /
elderly /
electrocardiogram parameters /
cardiac function /
prognosis
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