Latent Profile Analysis of Depression and Anxiety Symptoms in Adult Diabetic Patients

LI Na; YE Ying; WANG Honglin; JIN Songna; ZHOU Qiuhong

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Journal of Hunan Normal University(Medical Science) ›› 2025, Vol. 22 ›› Issue (6) : 86-92.

Clinical Medicine

Latent Profile Analysis of Depression and Anxiety Symptoms in Adult Diabetic Patients

LI Na¹, YE Ying², WANG Honglin¹, JIN Songna¹, ZHOU Qiuhong¹

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Abstract

Objective To explore the potential categories and influencing factors of depression and anxiety symptoms in adult diabetic patients. Methods A convenience sampling method was used to select 505 adult diabetic patients from 15 hospitals in Changsha, Hunan Province, based on inclusion and exclusion criteria. Data were collected through a self-designed general information questionnaire, Patient Health Questionnaire, and Generalized Anxiety Disorder. Mplus 8.3 software was used for potential profile analysis, and the potential categories of depression and anxiety symptoms of patients were explored in combination with relevant indicators. SPSS 27.0 software was used to conduct chi square test and multivariate logistic regression to analyze the influencing factors of different categories. Results Depression and anxiety symptoms in adult diabetic patients can be classified into three potential categories: mild depression and anxiety group (C1, 61.0%), moderate depression and anxiety with somatic symptoms group (C2, 30.5%), and severe depression and anxiety group (C3, 8.5%). Logistic regression analysis showed that taking group C1 as the reference group, female patients (OR=1.596, 95% CI: 1.063-2.399) were more likely to belong to group C2; patients living alone (OR=2.964, 95% CI: 1.375-6.390) were more likely to belong to group C3; patients with complications (OR=0.362, 95% CI: 0.169-0.744) and family monthly income>5 000 yuan (OR=0.300, 95% CI: 0.123-0.734) were less likely to belong to group C3. Conclusion Depression and anxiety symptoms in adult diabetic patients can be classified into three potential categories: mild depression and anxiety group: moderate depression and anxiety with somatic symptoms group, and severe depression and anxiety group, and were affected by gender, whether living alone, family monthly income, and complications. Medical staff should develop targeted psychological interventions and health guidance for diabetic patients based on their specific depression and anxiety subgroups.

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diabetes mellitus / depression / anxiety / latent profile analysis

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LI Na, YE Ying, WANG Honglin, JIN Songna, ZHOU Qiuhong. Latent Profile Analysis of Depression and Anxiety Symptoms in Adult Diabetic Patients[J]. Journal of Hunan Normal University(Medical Science). 2025, 22(6): 86-92

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