Objective The aim of this study is to analyze the impact and significance of Alzheimer's disease (AD) patients on caregiver burden, psychological status and quality of life from the perspective of Precision Psychological Capital Intervention (P-PCI). Methods Patients diagnosed with AD and their caregivers from our hospital between May 2019 and October 2022 were enrolled in the study, and all patients underwent conventional treatment for AD. The patients and their caregivers were divided into a control group (n=37), who underwent usual care, and an observation group (n=41), who underwent P-PCI on top of that, using a randomized numerical table. The psychological status of the carers was assessed by the positive psychological-capital questionnaire (PPQ), the readiness of the carers was assessed by the caregiver preparedness scale (CPS), the caring capacity of the carers was assessed by the family caregiver task inventory (FCTI), the carer burden was assessed by the caregiver burden inventory (CBI), the carer's social support was assessed by the social support rating scale (SSRS), and the WHOQOL-BREF assessed patient/carer quality of survival. Results After the intervention, compared with the Control group, the observation group: (1) showed a significant upward trend in PPQ dimensions: PPQ dimensions: self-efficacy, optimism, resilience, and hope, as well as the total score; (2) showed an upward trend in CPS, and an even more pronounced downward trend in FCTI; (3) showed a significant upward trend in CBI dimensions: time-dependent, developmentally limited, physical, social, and emotional load scores, as well as a significant downward trend in the total score; (4) showed a significant upward trend in all SSRS dimensions: a more pronounced upward trend in the objective support, subjective support, and utilisation of support scores, as well as in the total score; (5) showed a significant upward trend in WHOQOL-BREF score in caregiver's and patient's of all dimensions: trend in the physiological, psychological, social relationship, and environmental were more pronounced upward. Conclusion P-PCI can reduce the burden of caregiving and improve the quality of life of caregivers of patients with AD by effectively enhancing their psychological capital, which in turn leads to improved quality of life for patients.
Key words
precision psychological capital intervention /
psychological capital /
Alzheimer's disease /
caregiver burden /
social support
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References
[1] BLEIBEL M, EL C A, SADIER N S, et al.The effect of music therapy on cognitive functions in patients with Alzheimer’s disease: a systematic review of randomized controlled trials[J]. Alzheimers Res Ther, 2023, 15(1): 65.
[2] ROY S K, WANG J J, XU Y M.Effects of exercise interventions in Alzheimer's disease: A meta-analysis[J]. Brain Behav, 2023, 13(7): e3051.
[3] REN R, QI J, LIN S, et al.The China Alzheimer Report 2022[J]. Gen Psychiatr, 2022, 35(1): e100751.
[4] DUBOIS B, LOPEZ-ARRIETA J, LIPSCHITZ S, et al.Masitinib for mild-to-moderate Alzheimer's disease: results from a randomized, placebo-controlled, phase 3, clinical trial[J]. Alzheimers Res Ther, 2023, 15(1): 39.
[5] LOPEZ-ORTIZ S, LISTA S, VALENZUELA P L, et al.Effects of physical activity and exercise interventions on Alzheimer's disease: an umbrella review of existing meta-analyses[J]. J Neurol, 2023, 270(2): 711-725.
[6] 石玲琍, 彭超华, 张诗怡. 非药物干预对阿尔茨海默病患者照顾者负担影响系统评价的再评价[J]. 护理学杂志, 2024, 39(07): 104-108.
[7] ZHOU S, CHEN S, LIU X, et al.Physical Activity Improves Cognition and Activities of Daily Living in Adults with Alzheimer's Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials[J]. Int J Environ Res Public Health, 2022, 19(3): 1216.
[8] CHIRACU A, COSMA G A, STEPAN A R, et al.Psychological capital, quality of life, and well-being in mother caregivers of individuals with down syndrome[J]. Front Psychol, 2023, 14: 1145104.
[9] CHOI N G, DINITTO D M.Internet use among older adults: association with health needs, psychological capital, and social capital[J]. J Med Internet Res, 2013, 15(5): e97.
[10] HAZAN-LIRAN B, MILLER P.Psychological capital's mediation of anxiety-related patterns of thinking and academic adjustment among university students[J]. J Am Coll Health, 2025, 73(2): 673-683.
[11] 何丽青, 张茜, 郑贝贝, 等. 二元疾病管理理论在慢性心力衰竭病人及其照顾者中的应用进展[J]. 护理研究, 2022, 36(17): 3111-3115.
[12] 郭万鹏, 武文贤, 栗林. 基于二元疾病管理理论的出院准备服务方案在A型主动脉夹层术后病人中的应用[J]. 护理研究, 2024, 38(11): 2002-2008.
[13] MOU H, LAM S K K, CHIEN W T. The effects of a family-focused dyadic psychoeducational intervention for stroke survivors and their family caregivers: A randomised controlled trial[J]. Int J Nurs Stud, 2023, 143: 104504.
[14] 李占霞, 黄嘉琳, 张晨. 基于心理资本理论的干预对血液透析室护理人员工作投入状况的影响[J]. 贵州医药, 2021, 45(01): 149-151.
[15] 田金洲, 解恒革, 王鲁宁, 等. 中国阿尔茨海默病痴呆诊疗指南 (2020年版)[J]. 中华老年医学杂志, 2021, 40(3): 269-283.
[16] 孙倩倩, 梅永霞, 王文娜, 等. 脑卒中患者夫妻心理资本干预方案的构建[J]. 护理学杂志, 2024, 39(09): 103-107.
[17] JIANG Y, CHI J, WANG L, et al.Online communication and positive psychological capital of college students in China: the mediating role of online social support[J]. BMC Psychol, 2023, 11(1): 277.
[18] UHM K E, JUNG H, WOO M W, et al.Influence of preparedness on caregiver burden, depression, and quality of life in caregivers of people with disabilities[J]. Front Public Health, 2023, 11: 1153588.
[19] YAN Z, LIU F, LIN X P, et al.WeChat-based remote follow-up management alleviates the home care burden and anxiety of parents of premature infants: Randomized controlled study[J]. Child Care Health Dev, 2022, 48(4): 651-657.
[20] SHAFIEZADEH A, HERAVI-KARIMOOI M, MIRZAEE A, et al.Psychometric characteristics of the Iranian Caregiver Burden Inventory (CBI) in caregivers of elderly patients with Alzheimer[J]. Health Qual Life Outcomes, 2020, 18(1): 255.
[21] LIU M, QIN F, WANG D.A study of the mediating effect of social support on self-disclosure and demoralization in Chinese older adult homebound breast cancer patients[J]. Front Psychol, 2024, 15: 1365246.
[22] ARCHULETA A J, PROST S G, GOLDER S. Psychometric properties of the WHOQOL-BREF in a population of older adults in prison: measuring quality of life in a carceral setting[J]. Int J Prison Health, 2023, ahead-of-print: 668-681.
[23] YAZDANMANESH M, ESMAEILI R, NASIRI M, et al.Relieving care burden and promoting health-related quality of life for family caregivers of elderly people with Alzheimer's disease via an empowerment program[J]. Aging Clin Exp Res, 2023, 35(1): 73-83.
[24] LIAO X, HUANG Y, ZHANG Z, et al.Factors associated with health-related quality of life among family caregivers of people with Alzheimer's disease[J]. Psychogeriatrics, 2020, 20(4): 398-405.
[25] LEE M, RYOO J H, CROWDER J, et al.A systematic review and meta-analysis on effective interventions for health-related quality of life among caregivers of people with dementia[J]. J Adv Nurs, 2020, 76(2): 475-489.
[26] 张彩虹, 刘慧敏, 龚玉枝, 等. 视频微课健康教育模式在压力性损伤患者居家照顾者中的应用[J]. 护理学杂志, 2020, 35(21): 12-15.
[27] 张晶晶, 姜素兰, 倪莹莹. 老年颅内动脉瘤破裂患者心理状况及其与照顾者负担的相关性研究[J]. 海军医学杂志, 2022, 43(04): 411-416.
[28] NEMCIKOVA M, KATRENIAKOVA Z, NAGYOVA I.Social support, positive caregiving experience, and caregiver burden in informal caregivers of older adults with dementia[J]. Front Public Health, 2023, 11: 1104250.
[29] LI L, WISTER A V, LEE Y, et al.Transition Into the Caregiver Role Among Older Adults: A Study of Social Participation and Social Support Based on the Canadian Longitudinal Study on Aging[J]. J Gerontol B Psychol Sci Soc Sci, 2023, 78(8): 1423-1434.
[30] 万胤辰, 王招娣, 吴坤, 等. 照顾能力干预方案在晚期肺癌患者家庭照顾者中的应用研究[J]. 中华护理杂志, 2024, 59(15): 1824-1831.
[31] 刘杏, 周玉梅, 徐惠丽, 等. 中青年重症脑卒中患者主要照顾者预期性悲伤影响因素的结构方程模型构建[J]. 中国康复理论与实践, 2024, 30(04): 454-461.