Analysis of the incidence and susceptibility factors of pulmonary infection in patients with spinal injury and paraplegia

YANG Kaichao; HUANG Jianying; GENG Lei; WANG Xue

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Journal of Hunan Normal University(Medical Science) ›› 2025, Vol. 22 ›› Issue (3) : 69-72.

Analysis of the incidence and susceptibility factors of pulmonary infection in patients with spinal injury and paraplegia

YANG Kaichao¹, HUANG Jianying¹, GENG Lei¹, WANG Xue²

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Abstract

Objective To analyze the incidence and susceptibility factors of pulmonary infection in patients with spinal injury and paraplegia. Methods The clinical data of 106 patients with spinal injury and paraplegia admitted to the hospital from January 2023 to December 2024 were retrospectively analyzed. Patients enrolled were divided into the pulmonary infection group (n=42) and the non-pulmonary infection group (n=64) according to whether they had developed pulmonary infection. Univariate and multivariate logistic regression analyses were used to screen the risk factors for pulmonary infection in patients with spinal injury and paraplegia. ROC curve was used to evaluate the predictive value. Results Logistic regression analysis results showed that age (OR=1.103, 95%CI: 1.031-1.181), high paraplegia (OR=7.288, 95%CI: 1.246-42.643), MNA-SF score (OR=0.650, 95%CI: 0.489-0.862), and mechanical ventilation (OR=3.997, 95%CI: 1.356-11.778) were independent risk factors for pulmonary infection in patients with spinal injury and paraplegia. ROC analysis showed that the AUC value of combined prediction with the four factors was 0.870 and Youden index was 0.653. The values were significantly higher than those of separate prediction with each factor (Z=4.002, 4.088, 3.538, 4.116). Conclusion The incidence of pulmonary infection is relatively high in patients with spinal injury and paraplegia. Advanced age, high paraplegia, low MNA-SF score, and mechanical ventilation are susceptible factors for pulmonary infection in patients with spinal injury and paraplegia.

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spinal injury / paraplegia / pulmonary infection / incidence / risk factor

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YANG Kaichao, HUANG Jianying, GENG Lei, WANG Xue. Analysis of the incidence and susceptibility factors of pulmonary infection in patients with spinal injury and paraplegia[J]. Journal of Hunan Normal University(Medical Science). 2025, 22(3): 69-72

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