Objective To evaluate the efficacy and safety of uterine massage combined with oxytocin in preventing postpartum hemorrhage (PPH) in high-risk parturients. Methods A prospective randomized controlled trial was conducted, enrolling 400 high-risk parturients who delivered in the obstetrics department of a tertiary hospital between January 2019 and December 2023. The participants were randomly divided into a control group and an observation group, with 200 cases in each group. The control group received routine oxytocin therapy, while the observation group received uterine massage in addition to oxytocin therapy. The primary outcomes measured included the duration of the third stage of labor, blood loss within 2 hours and 24 hours postpartum, and hemostasis time. Secondary outcomes included postpartum coagulation function, hemoglobin levels 1 hour postpartum, uterine involution, complication rates, hospital stay duration, and patient satisfaction. Results Compared with the control group, the observation group showed significant improvements in the duration of the third stage of labor (8.33±2.81 minutes vs 10.51±3.22 minutes, P<0.001), blood loss within 2 hours postpartum (187.45±46.52 mL vs 250.62±52.85 mL, P<0.001), blood loss within 24 hours postpartum (357.83±80.76 mL vs 455.23±98.42 mL, P<0.001), and hemostasis time (38.27±8.95 minutes vs 43.59±10.25 minutes, P<0.001). Additionally, the observation group experienced faster uterine involution, shorter hospital stays, and higher patient satisfaction. There was no significant difference in complication rates between the two groups. Conclusion Uterine massage combined with oxytocin is significantly more effective than oxytocin alone in preventing postpartum hemorrhage in high-risk parturients, with good safety. This combined treatment method has valuable potential for clinical application.
Key words
postpartum hemorrhage /
uterine massage /
oxytocin /
high-risk parturients
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