Analysis of Fatigue Risk Factors and Intervention Strategies in Patients with Acute Pancreatitis

ZHANG Chi, WANG Fang, ZHANG Lei

Journal of Hunan Normal University(Medical Science) ›› 2025, Vol. 22 ›› Issue (1) : 154-157.

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Journal of Hunan Normal University(Medical Science) ›› 2025, Vol. 22 ›› Issue (1) : 154-157.
Clinical Medicine

Analysis of Fatigue Risk Factors and Intervention Strategies in Patients with Acute Pancreatitis

  • ZHANG Chi1, WANG Fang2, ZHANG Lei3
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Abstract

Objective To explore the risk factors of fatigue in patients with acute pancreatitis, and put forward intervention countermeasures. Methods 153 patients with acute pancreatitis admitted to our hospital from January 2024 to June 2024 were taken as the observation objects, and they were divided into non-fatigue group (9 points<FSS score<36 points) and fatigue group (FSS score ≥36 points) according to the score of the fatigue severity scale (FSS). The risk factors affecting their fatigue were analyzed by univariate and multivariate analysis methods, and a risk prediction model was established. Results There were statistical differences in age, hospitalization days and acute physiology and chronic health evaluation Ⅱ (APACHE Ⅱ) score between the two groups. Serum C-reactive protein (CRP), mean platelet volume (MPV) and red cell distribution width (RDW) levels in fatigue group were higher than those in non-fatigue group. Age ≥60 years old (OR=2.264, 95% CI: 1.411-3.630), high APACHE Ⅱ score (OR=2.106, 95% CI: 1.489-2.980), serum CRP (OR=2.298, 95% CI: 1.200).95% CI: 1.180-2.614), high RDW level (OR=1.917, 95% CI: 1.564-2.351) and long hospital stay (OR=1.923, 95% CI: 1.310-2.824) all affect the fatigue of patients with acute pancreatitis. The risk prediction model constructed in this study predicts the risk of fatigue in patients with acute pancreatitis with AUC of 0.895(0.820-0.969), sensitivity of 93.75% and specificity of 84.72%. Conclusion The fatigue risk of patients with acute pancreatitis is related to age, severity of illness, inflammatory index and length of hospital stay. The risk prediction model constructed in this study can effectively predict fatigue risk with high sensitivity and specificity. Medical staff should formulate intervention measures against these factors to reduce patient fatigue.

Key words

acute pancreatitis / fatigue / risk factors / intervention countermeasures

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ZHANG Chi, WANG Fang, ZHANG Lei. Analysis of Fatigue Risk Factors and Intervention Strategies in Patients with Acute Pancreatitis[J]. Journal of Hunan Normal University(Medical Science). 2025, 22(1): 154-157

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