Objective To assess the initial treatment outcomes of chronic dacryocystitis using modified endoscopic dacryocystorhinostomy (En-DCR) with Befulxu gel. Methods This study enrolled 92 patients with chronic dacryocystitis treated at the People's Hospital affiliated with Jiangsu University from October 2020 to October 2023. Patients were randomly assigned to either the reference group (n=46) or the combined group (n=46) using a random number table method. Both groups underwent modified En-DCR; the combined group additionally received Beifushu gel packing at the anastomotic site. Clinical efficacy, lacrimal duct function and symptom assessment, postoperative recovery, patient satisfaction, and quality of life were compared between the two groups. Results The overall effectiveness and satisfaction rates were higher in the combined group compared to the reference group. Post-treatment, the combined group exhibited lower scores for tear overflow, higher tear film breakup time (BUT), and better patency of the lacrimal duct than the reference group. Six months after treatment, the combined group showed smaller anastomosis site areas, lower granulation tissue detection rates, and lower recurrence rates, along with higher SF-36 scores than the reference group. Conclusion Modified En-DCR combined with Befulxu gel packing significantly improves the patency of the lacrimal duct postoperatively, enhances tear secretion, and is safe, thus meriting broader clinical application.
Key words
chronic dacryocystitis /
modified endoscopic dacryocystorhinostomy /
beifuji gel /
early efficacy
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