Objective To investigate the effects of cisatracurium on Muscle relaxation and postoperative recovery in patients undergoing inhalation anesthesia and intravenous anesthesia. Methods 84 cases of patients with under general anesthesia were collected adn randomly divided into Sevoflurane inhalation anesthesia group (Inhalation anesthesia group) and Propofol-remifentanil group (intravenous anesthesia group), The cisatracurium infusion rate, recovery index and postoperative recovery were recorded. Results With the maintenance of a neuromuscular blockade, the infusion rate was significantly lower in sevoflurane group than in propofol-remifentanil group, In the inhaled anesthesia group, the time of eye opening and the time of shaking call was shorter than that of intravenous anesthesia. The incidence of delayed awakening in the inhaled anesthesia group was lower than that in the intravenous anesthesia group (2.38% / 7.14%), (11.90% / 2.38%), the difference was statistically significant. Conclusion Inhalation anesthesia with propofol-propofol-remifentanyl total intravenous anesthesia can be time-dependent enhancement of cisatracurium-induced muscle relaxation effect, and the former is better than the latter, while inhalation anesthesia is more conducive to patients Wake, reduce agitation, But prone to restlessness, the clinical application of patients under a reasonable choice.