Effect of furosemide, digitalis, canola combined with BIPAP of noninvasive ventilation on COPD with left ventricular failureand pulmonary edema

Li Xue-feng

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Journal of Hunan Normal University(Medical Science) ›› 2018, Vol. 15 ›› Issue (3) : 110-113.

Effect of furosemide, digitalis, canola combined with BIPAP of noninvasive ventilation on COPD with left ventricular failureand pulmonary edema

Li Xue-feng

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Abstract

Objective To observe the clinical effect of BIPAP of noninvasive ventilation in the treatment of COPD with left ventricular failure and pulmonary edema on the basis of conventional diuresis, cardiac and central excitatory drugs such as furosemide, digitalis and canola. Methods The clinical data of 135 patients with COPD complicated with left heart failure pulmonary edema from January 1, 2014 to December 31, 2016 in our hospital were retrospectively analyzed, and the patients were divided into observation group (n=68) and control group (n=67) according to different treatment methods. Among them, the control group was treated with furosemide, digitalis, canola and other conventional diuresis, cardiac and central excitatory drugs for treatment, while the observation group added BiPAP treatment based on the control. The general clinical indicators at 2 hours after the treatment, the treatment effect, cardiac function improvement and of lung function improvement at 3 months after the treatment of the two groups were compared. Results Two hours after the treatment, the levels of SBP, SDP, HR, PaO₂, PaCO₂, SaO₂ and Brog dyspnea score in the observation group were significantly better than those in the control group. Three months after the treatment, the total effective rate was 92.65% in the observation group, which was significantly higher than 79.10% in the control group; the cardiac parametersof LVEF, 6 min walking distance and BNP level in the observation group were significantly better than those in the control group, the lung function indexes of FEV₁, FEV₁/FVC and FEV₁% Pred in the observation group were significantly better than those in the control group. Conclusion For patients with COPD complicated with left heart failure and pulmonary edema, BiPAP treatment combined with conventional diuresis, cardiac and central excitatory drugs such as furosemide, digitalis and canola can significantly rapidlyrelieve the clinical symptoms of patients, improve the patient’s heart and lung function, and the treatment effect is better.

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diuretic

/ digitalis / noninvasive bi-level positive pressure ventilation / COPD combined with left heart failure

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Li Xue-feng.

Effect of furosemide, digitalis, canola combined with BIPAP of noninvasive ventilation on COPD with left ventricular failureand pulmonary edema

[J]. Journal of Hunan Normal University(Medical Science). 2018, 15(3): 110-113

References

［1］单湘湘, 周建平, 范仁根, 等. 慢性阻塞性肺疾病合并肺源性心脏病危险相关因素分析［J］. 国际老年医学杂志, 2015(4): 162-165.

［2］ Shrikrishna D, Hopkinson N S. Chronic obstructive pulmonary disease: consequences beyond the lung［J］. Clinical Medicine, 2012, 12(1): 71-74.

［3］金怡, 徐中菊. BiPAP呼吸机治疗COPD急性加重期合并急性左心衰患者的疗效观察［J］. 实用临床医药杂志, 2015, 19(24): 20-22.

［4］沈楚婕, 张伟. 慢性阻塞性肺疾病早期筛查方法及临床意义［J］. 国际呼吸杂志, 2015, 35(15): 1144-1148.

［5］李虹, 李一丹, 吕秀章, 等. 肺超声联合超声心动图评价左心衰患者的临床研究［J］. 中国超声医学杂志, 2016, 32(8): 696-699.

［6］郭丽平, 付秀华, 杨倩, 等. 呼吸功能训练对稳定期COPD患者肺功能的影响［J］. 内蒙古医科大学学报, 2014(s1): 27-30.

［7］何谦, 何亚荣, 曹钰. 无创正压通气在老年慢性阻塞性肺疾病合并急性左心衰竭患者中的疗效分析［J］. 华西医学, 2015(6): 1007-1010.

［8］ Fletcher E, Nolan C M, Canavan J L, et al. COPD and co-existent chronic heart failure (CHF): Response to pulmonary rehabilitation (PR) ［J］. European Respiratory Journal, 2016, 48(suppl 60): PA3589.

［9］ Oliveira M F, Alencar M C, Arbex F, et al. Effects of Heart Failure on Cerebral Blood Flow in COPD: Rest and Exercise. ［J］. Respiratory Physiology & Neurobiology, 2016, 221: 41.

［10］杨波, 田小溪. 持续气道正压通气治疗急性左心衰并呼吸衰竭临床观察［J］. 临床急诊杂志, 2015(7): 543-544.

［11］韩秀平, 贺钰梅, 汪丽丽, 等. BiPAP对慢性心力衰竭合并睡眠呼吸暂停综合征患者的血管内皮功能及心肺功能的影响［J］. 医学综述, 2016, 22(21): 4289-4291.

［12］陈庆. BiPAP无创呼吸机治疗急性左心衰竭患者疗效观察［J］. 中国医药导刊, 2016, 18(4): 365-366.

［13］杨莉, 白引珠. 双水平正压通气治疗急性心源性肺水肿的临床观察及护理［J］. 实用临床医药杂志, 2015, 19(18): 13-15.

［14］陈俊, 顾建华, 朱旖. BIPAP无创正压通气救治老年重症肺炎并发左心衰竭的疗效分析［J］. 实用老年医学, 2016(2): 136-138.

［15］朴希君. 护理干预对BiPAP呼吸机治疗COPD合并呼吸衰竭患者肺功能的影响［J］. 广西医科大学学报, 2015, 32(5): 857-859.