慢性心力衰竭患者的生物、社会、心理因素对睡眠质量的影响

肖愿, 李东雅, 朱云龙, 王迎春, 胡礼玉, 龙伟军, 李奋威

湖南师范大学学报医学版 ›› 2026, Vol. 23 ›› Issue (1) : 106-114.

PDF(2222 KB)
PDF(2222 KB)
湖南师范大学学报医学版 ›› 2026, Vol. 23 ›› Issue (1) : 106-114.
临床医学

慢性心力衰竭患者的生物、社会、心理因素对睡眠质量的影响

  • 肖愿1,2, 李东雅1, 朱云龙2, 王迎春2, 胡礼玉2, 龙伟军2, 李奋威2
作者信息 +

Sleep Disturbances in Patients with Chronic Heart Failure: A Cross-Sectional Study on Prevalence and Correlates from Bio-Psycho-Social Perspectives

  • XIAO Yuan1,2, LI Dongya1, ZHU Yunlong2, WANG Yingchun2, HU Liyu2, LONG Weijun2, LI Fenwei2
Author information +
文章历史 +

摘要

目的 探讨慢性心力衰竭(chronic heart failure,CHF)患者睡眠障碍的发生情况,并分析其与生物、社会、心理等多维度因素的相关性,为临床干预提供依据。方法 采用回顾性横断面研究设计,选取2023年3月—2025年3月在湘潭市第二人民医院心内科收治的慢性心力衰竭患者作为调查对象,共纳入396例CHF患者。使用匹兹堡睡眠质量指数(Pittsburgh sleep quality index,PSQI)、心力衰竭躯体知觉量表(heart failure somatic perception scale,HFSPS)、医院焦虑抑郁量表(hospital anxiety and depression scale,HADS)、社会支持评定量表(social support rating scale,SRSS)、家庭关怀度指数量表(family adaptation partnership growth affection resolve index,APGAR)评估慢性心衰患者睡眠情况、躯体感知、焦虑或抑郁状态及家庭关怀度,将患者分为睡眠障碍组(PSQI>7分)与无睡眠障碍组(PSQI≤7分)。同时收集患者一般资料、临床特征等,行单因素、多因素Logistic回归及中介效应分析。结果 396例CHF患者中,282例(71.21%)存在睡眠障碍。单因素分析显示,年龄、自我健康评价、纽约心力衰竭分级、社会支持评定量表评分、家庭关怀度指数量表评分及心力衰竭躯体感觉量表评分与睡眠障碍显著相关。多因素分析进一步表明,自我健康评价差(OR=3.485,95% CI:2.155~5.788)是睡眠障碍的独立危险因素,而较高的家庭关怀度(OR=0.869,95% CI:0.780~0.965)是保护因素。中介分析进一步表明,自我健康评价在纽约心力衰竭分级与睡眠障碍间起完全中介作用,存在遮掩效应。结论 CHF患者睡眠障碍发生率较高,其发生与自我健康评价和家庭支持密切相关,且自我健康评价是客观心功能影响睡眠的关键中介。在临床护理中,应重视对患者主观健康感受的评估与心理疏导,并加强家庭支持系统的构建,以改善患者的睡眠质量。

Abstract

Objective To investigate the prevalence of sleep disturbances in patients with Chronic Heart Failure (CHF) and analyze their correlations with biological, social, and psychological multidimensional factors, thereby providing a basis for clinical intervention. Methods A retrospective cross-sectional study was conducted. A total of 396 CHF patients admitted to the Department of Cardiology, Xiangtan Second People's Hospital between March 2023 and March 2025 were enrolled. Sleep quality, somatic perception, anxiety/depression status, social support, and family function were assessed using the Pittsburgh Sleep Quality Index (PSQI), Heart Failure Somatic Perception Scale (HFSPS), Hospital Anxiety and Depression Scale (HADS), Social Support Rating Scale (SSRS), and Family APGAR Index, respectively. Patients were divided into a sleep disturbance group (PSQI≥7) and a non-sleep disturbance group (PSQI<7). General patient data and clinical characteristics were collected. Univariate analysis, multivariate Logistic regression, and mediation effect analysis were performed. Results Among the 396 CHF patients, 282(71.21%) had sleep disturbances. Univariate analysis showed that age, self-rated health, New York Heart Association (NYHA) functional classification, SSRS score, Family APGAR score, and HFSPS score were significantly associated with sleep disturbances. Multivariate analysis further indicated that poor self-rated health (OR=3.485, 95% CI: 2.155-5.788) was an independent risk factor for sleep disturbances, while higher family support (OR=0.869, 95% CI: 0.780-0.965) was a protective factor. Mediation analysis revealed that self-rated health played a complete mediating role in the relationship between NYHA classification and sleep disturbances, indicating a suppression effect. Conclusion The incidence of sleep disturbances is high among CHF patients. Their occurrence is closely related to self-rated health and family support, with self-rated health being a key mediator through which objective cardiac function affects sleep. In clinical nursing practice, emphasis should be placed on assessing and providing psychological guidance regarding patients' subjective health perceptions, as well as strengthening the family support system, to improve patients' sleep quality.

关键词

慢性心力衰竭 / 睡眠障碍 / 自我健康评价 / 心理社会因素

Key words

chronic heart failure / sleep disturbance / self-rated health / psychosocial factors

引用本文

导出引用
肖愿, 李东雅, 朱云龙, 王迎春, 胡礼玉, 龙伟军, 李奋威. 慢性心力衰竭患者的生物、社会、心理因素对睡眠质量的影响[J]. 湖南师范大学学报医学版. 2026, 23(1): 106-114
XIAO Yuan, LI Dongya, ZHU Yunlong, WANG Yingchun, HU Liyu, LONG Weijun, LI Fenwei. Sleep Disturbances in Patients with Chronic Heart Failure: A Cross-Sectional Study on Prevalence and Correlates from Bio-Psycho-Social Perspectives[J]. Journal of Hunan Normal University(Medical Science). 2026, 23(1): 106-114
中图分类号: R749.7   

参考文献

[1] 王华, 梁延春. 中国心力衰竭诊断和治疗指南2018[J]. 中华心血管杂志, 2018, 46(10): 760-789.
[2] 刘明波, 何新叶, 杨晓红, 等. 《中国心血管健康与疾病报告2023》概要 (心血管疾病流行及介入诊疗状况)[J]. 中国介入心脏病学杂志, 2024, 32(10): 541-550.
[3] 王华, 刘宇佳, 杨杰孚. 心力衰竭流行病学[J]. 临床心血管病杂志, 2023, 39(04): 243-247.
[4] 邹云增, 王琦. 心力衰竭转化研究的新进展[J]. 临床心血管病杂, 2025, 41(01): 9-13.
[5] CONLEY S, FEDER SL, JEON S, et al.Daytime and nighttime sleep characteristics and pain among adults with stable heart failure[J]. J Cardiovasc Nurs, 2019, 34(5): 390-398.
[6] NAYYERI S, GOLAFROOZ M, SADEGHI H, et al.The effect of the partnership care model on the quality of sleep among patients with heart failure[J]. J Sabz Univ Med Sci, 2015, 22(3): 289-299.
[7] JANKAJOVA M, SINGH RB, HRISTOVA K, et al.Identification of pre-heart failure in early stages: the role of six stages of heart failure[J]. Diagnostics, 2024, 14(23): 2618.
[8] LALLUKKA T, SIVERTSEN B, KRONHOLM E, et al.Association of sleep duration and sleep quality with the physical, social, and emotional functioning among Australian adults[J]. Sleep Health, 2018, 4(2): 194-200.
[9] JEON S, REDEKER NS.Sleep disturbance, daytime symptoms, and functional performance in patients with stable heart failure: A mediation analysis[J]. Nurs Res, 2016, 65(4): 259-267.
[10] GARCIA S, ALOSCO ML, SPITZNAGEL MB, et al.Poor sleep quality and reduced cognitive function in persons with heart failure[J]. Int J Cardiol, 2012, 156: 248-249.
[11] NAING L, WINN T, RUSLI BN.Practical issues in calculating the sample size for prevalence studies[J]. Arch Orofac Sci, 2006, 1: 9-14.
[12] BUYSSE DJ, REYNOLDS CR, MONK TH, et al.The Pittsburgh sleep quality index: a new instrument for psychiatric practice and research[J]. Psychiatry Res, 1989, 28(2): 193-213.
[13] JURGENS CY.Somatic awareness, uncertainty, and delay in care-seeking in acute heart failure[J]. Res Nurs Health, 2006, 29(2): 74-86.
[14] CHEN C, FANG W, AN Y, et al.The multiple mediating effects of illness perceptions and coping strategies on the relationship between physical symptoms and depressive symptoms in patients with heart failure[J]. Eur J Cardiovasc Nurs, 2020, 19(2): 125-133.
[15] ZIGMOND AS, SNAITH RP.The hospital anxiety and depression scale[J]. Acta Psychiatr Scand, 1983, 67(6): 361-370.
[16] 范青, 季建林, 肖泽萍, 等. 综合医院焦虑抑郁量表在内科门诊病人中的应用[J]. 中国心理卫生杂志, 2010, 24(05): 325-328.
[17] SINEOS PE.The prevalence of alexithymic characteristics in psychosomatic patients[J]. Psychother Psychosom, 1973, 22(2-6): 255-262.
[18] SMILKSTEIN G.The Family APGAR: a proposal for a family function test and its use by physicians[J]. J Fam Pract, 1978, 6(6): 1231-1239.
[19] COWIE MR, LINZ D, REDLINE S, et al.Sleep disordered breathing and cardiovascular disease: JACC state-of-the-art review[J]. J Am Coll Cardiol, 2021, 78(6): 608-624.
[20] YEGHIAZARIANS Y, JNEID H, TIETJENS JR, et al.Obstructive sleep apnea and cardiovascular disease: a scientific statement from the American Heart Association[J]. Circulation, 2021, 144(3): e56-e67.
[21] JESSUP M, BROZENA S.Heart failure[J]. N Engl J Med, 2003, 348(20): 2007-2018.
[22] GEHLBACH BK, GEPPERT E.The pulmonary manifestations of left heart failure[J]. Chest, 2004, 125(2): 669-682.
[23] DZIERZEWSKI JM, DAUTOVICH N, RAVYTS S.Sleep and cognition in older adults[J]. Sleep Med Clin, 2018, 13(1): 93-106.
[24] SANTOS-ORLANDI AAD, OTTAVIANI AC, ALVES EDS, et al.Sleep quality of vulnerable elderly people: associated factors[J]. Rev Bras Enferm, 2024, 77(Suppl 3): e20230283.
[25] REIMER MA, FLEMONS WW.Quality of life in sleep disorders[J]. Sleep Med Rev, 2003, 7(4): 335-349.
[26] Wang LX, Yu PH, Zhang YX, et al.Psychological features of patients with obstructivesleep apnea-hypopnea syndrome and its intervention[J]. Nanfang J Nurs, 2005, 12(12): 4-6.
[27] TŐNNIES T, SCHLESINGER S, LANG A, et al. Mediation analysis in medical research[J]. Dtsch Arztebl Int, 2023, 120(41): 681-687.
[28] FLINT KM, SCHMIEGE SJ, ALLEN LA, et al.Health status trajectories among outpatientswith heart failure[J]. J Pain Symptom Manage, 2017, 53(2): 224-231.
[29] WANG TJ, LEE SC, TSAY SL, et al.Factors influencing heart failure patients' sleep quality[J]. J Adv Nurs, 2010, 66(8): 1730-1740.
[30] HE D, PAN M.Serial multiple mediators in the relationship between symp-tom burden and sleep quality among patients with heart failure[J]. Jpn J Nurs Sci, 2022, 19(4): e12489.
[31] BERRY RB.Fundamentals of Sleep Medicine[M]. Dhiladelphia: Saunders, 2012: 219-235.
[32] LI DK, WANG XT, LIU DW.Association between elevated central venous pressure and outcomes in critically ill patients[J]. Ann Intensive Care, 2017, 7(1): 83.
[33] SKOBEL E, NORRA C, SINHA A, et al.Impact of sleep-related breathing disorders on health-related quality of life in patients with chronic heart failure[J]. Eur J Heart Fail, 2005, 7(4): 505-511.
[34] JEON S, REDEKER NS.Sleep disturbance, daytime symptoms, and functional performance in patients with stable heart failure: a mediation analysis[J]. Nurs Res, 2016, 65(4): 259-267.
[35] MITCHELL HA, WEINSHENKER D.Good night and good luck: norepinephrine in sleep pharmacology[J]. Biochem Pharmacol, 2010, 79(6): 801-809.
[36] LIU K, LI B, LIAO X, et al.Exploring the association between beta-blockers use and sleep complaints in U. S. adults: an analysis of NHANES data (2011-2018)[J]. J Psychiatr Res, 2025, 189: 316-324.
[37] MCAINSH J, CRUICKSHANK JM.Beta-blockers and central nervous system side effects[J]. Pharmacol Ther, 1990, 46(2): 163-197.
[38] TIKHOMIROVA OV, ZYBINA NN, KOZHEVNIKOVA VV.Effects of prolonged use of β-adrenoblockers on melatonin secretion, sleep quality, and vascular brain damage[J]. Neurosci Behav Physiol, 2022, 52(4): 500-504.
[39] TABARA Y, CHIN K.Salt, diuretics, and obstructive sleep apnea[J]. Ann Am Thorac Soc, 2021, 18(12): 2101-2103.
[40] DUTTA P, SADRIA M, LAYTON AT.Influence of administration time and sex on natriuretic, diuretic, and kaliuretic effects of diuretics[J]. Am J Physiol Renal Physiol, 2023, 324(3): F274-F286.
[41] SHIINA K.Obstructive sleep apnea-related hypertension: a review of the literature and clinical management strategy[J]. Hypertens Res, 2024, 47(11): 3085-3098.

基金

湘潭市科技局指导性项目“基于循证构建慢性心衰患者睡眠管理方案的研究”(ZP-ZDJH2022018)

PDF(2222 KB)

Accesses

Citation

Detail

段落导航
相关文章

/