目的: 观察针刺联合循经点穴按摩、低度聚焦超声治疗哺乳期急性乳腺炎的临床疗效。方法: 选取2021年6月—2023年6月在中南大学湘雅三医院母乳喂养门诊治疗的150例哺乳期急性乳腺炎患者为研究对象。将患者按照随机数字法分为对照组（n=70）和观察组（n=80）。对照组仅进行头孢克肟常规消炎治疗,观察组采取针刺联合循经点穴按摩和低强度聚焦超声治疗。连续治疗7 d后,对比两组患者治疗前后乳腺腺体恢复情况、细胞炎性因子水平;同时对两组治疗前后中医证候积分、VAS评分、SF-36评分和治疗满意度评分进行比较;并根据症状、体征及炎症反应指标评价临床疗效。结果: ①治疗后二组乳腺腺体组织结构基本恢复,边界清晰,边缘饱满、间质回声均匀,观察组情况更佳;治疗后超声低回声不规则区域较治疗前明显减小,且治疗后观察组和对照组差异具有统计学意义;②二组白细胞计数（WBC）、中性粒细胞百分比（NE%）、白细胞介素-8（IL-8）、C反应蛋白（CRP）水平均明显降低,且观察组低于对照组;③治疗后,两组中医证候积分、VAS评分明显降低,且观察组低于对照组;④观察组总有效率96.25%,高于对照组总有效率85.71%。结论: 针刺联合循经点穴按摩、低强度聚焦超声治疗哺乳期急性乳腺炎疗效显著,具有较好的临床应用推广价值。
Abstract
Objective To explore the clinical efficacy of acupuncture combined with acupoint massage at meridian point and low intensity focused ultrasound therapy in the treatment of acute lactational mastitis. Methods A total of 150 patients with acute mastitis during lactation who received treatmnet at the Breastfeeding Clinic of Xiangya Third Hospital, Central South University, from June 2021 June to 2023 were selected as the research subjects. According to the patients’ treatment plans, They were divided into a control group (n=70) and an observation group (n=80). The control group received conventional anti-inflammatory treatment with cefixime, while the observation group received acupuncture combined with acupoint massage at meridian points and low intensity focused ultrasound (LIFU) treatment. After 7 days of continuous treatment, the recovery of mammary gland tissue and levels of inflammatory cytokines before and after treatment were compared between the two groups. Traditional Chinese medicine syndrome scores, Visual Analog Scale (VAS) scores, SF-36 scores, and treatment satisfaction scores were compared between the two groups. Clinical efficacy was evaluated based on symptoms, signs, and indicators of inflammatory response. Results After treatmnet, The mammary gland tissue structure in both groups wass basically normal, with clear boundaries, full edges, and homogennous interstitial echoes. The observation group showed better results. The area of ultrasound hypoechoic irregularity was significantly reduced after treatment compared with that before treatment, and the difference between the observation group and the control group after treatment was statistically significant. The white blood cell count (WBC), neutrophil percentage (NE%), interleukin-8(IL-8), and C-reactive protein (CRP) levels were significantly decreased in both groups after treatment, with the observation group showing lower levels than the control group. After treatmnet, The traditional Chinese medicine clinical symptom score and Visual Analog Scale (VAS) scores in both groups were significantly reduced, with the observation group showing lower scores than the control group, and the differences were statistically significant. The total effective rate in the observation group was 96.25%, which was higher than the total effective rate of 85.71% in the control group, and the difference was significant. Conclusion The combination of acupuncture combined with acupoint massage at meridian points and low intensity focused ultrasound shows significant efficacy in the treatment of acute lactational mastitis. This finding has certain guiding significance and practical application value.
关键词
针刺 /
循经点穴按摩 /
低强度聚焦超声 /
哺乳期急性乳腺炎
Key words
acupuncture /
meridian massage /
low intensity focused ultrasound /
acute mastitis during lactation
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基金
湖南省卫生健康委员会科研项目“经颅磁刺激对压力性尿失禁的作用机制”（S2021JJ31012）
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