顺式阿曲库铵在不同麻醉中对患者术后苏醒恢复及预后的影响

莫进海

湖南师范大学学报医学版 ›› 2018, Vol. 15 ›› Issue (3) : 66-68.

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湖南师范大学学报医学版 ›› 2018, Vol. 15 ›› Issue (3) : 66-68.
临床医学

顺式阿曲库铵在不同麻醉中对患者术后苏醒恢复及预后的影响

  • 莫进海
作者信息 +

Effects of cisatracurium on recovery and prognosis of postoperative awakening in different anesthesia for patients

  • Mo Jin-hai
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文章历史 +

摘要

目的:比较吸入麻醉与静脉麻醉对持续输注顺式阿曲库铵肌松效应及术后恢复的影响。方法:选择全麻下手术患者84例,随机分成七氟烷吸入麻醉组(吸入麻醉组)和丙泊酚-瑞芬太尼组(静脉麻醉组),各42例。记录顺式阿曲库铵输注速率、恢复指数及术后恢复情况等指标。结果:与初始输注速率比较,两组持续给药30~180 min 期间顺式阿曲库铵输注速率下降,且吸入麻醉组输注速率显著低于静脉麻醉组;吸入麻醉组患者呼之睁眼时间、呼之握È时间均较静脉麻醉组所需时间短;吸入麻醉组苏醒延迟发生率均低于静脉麻醉组(2.38%/7.14%),但躁动发生率高于静脉麻醉组(11.90%/2.38%),差异显著。结论:七氟烷吸入麻醉与丙泊酚-瑞芬太尼全凭静脉麻醉均能呈时间依赖式提升顺式阿曲库铵肌松效果,且前者的优于后者,同时吸入麻醉更有利于患者苏醒,但易发生躁动,临床应用中可根据患者情况合理选择。

Abstract

Objective To investigate the effects of cisatracurium on Muscle relaxation and postoperative recovery in patients undergoing inhalation anesthesia and intravenous anesthesia. Methods 84 cases of patients with under general anesthesia were collected adn randomly divided into Sevoflurane inhalation anesthesia group (Inhalation anesthesia group) and Propofol-remifentanil group (intravenous anesthesia group), The cisatracurium infusion rate, recovery index and postoperative recovery were recorded. Results With the maintenance of a neuromuscular blockade, the infusion rate was significantly lower in sevoflurane group than in propofol-remifentanil group, In the inhaled anesthesia group, the time of eye opening and the time of shaking call was shorter than that of intravenous anesthesia. The incidence of delayed awakening in the inhaled anesthesia group was lower than that in the intravenous anesthesia group (2.38% / 7.14%), (11.90% / 2.38%), the difference was statistically significant. Conclusion Inhalation anesthesia with propofol-propofol-remifentanyl total intravenous anesthesia can be time-dependent enhancement of cisatracurium-induced muscle relaxation effect, and the former is better than the latter, while inhalation anesthesia is more conducive to patients Wake, reduce agitation, But prone to restlessness, the clinical application of patients under a reasonable choice.

关键词

苏醒
/ 顺式阿曲库铵 / 丙泊酚 / 瑞芬太尼 / 七氟烷  /

Key words

awakening
/ cisatracurium / propofol / remifentanil / sevoflurane

引用本文

导出引用
莫进海.
顺式阿曲库铵在不同麻醉中对患者术后苏醒恢复及预后的影响
[J]. 湖南师范大学学报医学版. 2018, 15(3): 66-68
Mo Jin-hai.
Effects of cisatracurium on recovery and prognosis of postoperative awakening in different anesthesia for patients
[J]. Journal of Hunan Normal University(Medical Science). 2018, 15(3): 66-68

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顺式阿曲库铵在不同麻醉中对患者术后苏醒恢复及预后的影响
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