超声测定肾动脉阻力指数在脓毒症合并急性肾损伤患者中的作用

PDF(1970 KB)

湖南师范大学学报医学版 ›› 2018, Vol. 15 ›› Issue (3) : 116-119.

临床医学

超声测定肾动脉阻力指数在脓毒症合并急性肾损伤患者中的作用

赵　鹏，刘　星，孟祥安，李冰冰，王会迟，赵　娟，马文聪，田静朴，孙　昊

作者信息 +

Role of renal arterial resistance index in patients with sepsis complicated with acute kidney injury

Zhao Peng, Liu Xing, Meng Xiang-an, Li Bing-bing, Wang Hui-chi, Zhao Juan, Ma Wen-cong, Tian Jing-pu, Sun Hao

Author information +

文章历史 +

摘要

目的：探讨超声测定肾动脉阻力指数（RRI）在脓毒症合并急性肾损伤（AKI）患者中的作用。方法：选取2014年3月~2017年2月ICU收治的危重患者中确诊为脓毒症的150例作为观察对象，根据KDIGO标准分为四组，未发生AKI的51例作为A组，AKI 1期的43例作为B组，AKI 2期的35例作为C组，AKI 3期的21例作为D组。通过超声测定患者的RRI，免疫比浊法测定Scys C和Ucys C，ELISA法测定SCr。对所有数据进行统计分析。结果：A组第1d RRI、Scys C、Ucys C及SCr与B组均无明显差别，第2、3d则存在明显差别；C组第1、2、3d RRI、Scys C、Ucys C及SCr均明显高于A组和B组；D组第1、2、3d RRI、Scys C、Ucys C及SCr均明显高于其他三组；相关分析显示，RRI与Scys C、Ucys C及SCr各个时间均呈正相关。结论：超声测定可有效的反应脓毒症合并AKI患者肾损害程度。

Abstract

Objective to investigate the role of renal artery resistance index (RRI) in patients with sepsis complicated with acute kidney injury (AKI). Method Critically ill patients diagnosed from March 2014 -2017 year in February from ICU in 150 cases of sepsis as observation object, according to the KDIGO standards are divided into four groups, 51 cases without AKI as group A, 43 cases of AKI 1 as B group, 35 cases of AKI 2 as C group, 21 cases of AKI the 3 stage is the D group. The RRI patients were determined by ultrasound, Scys C and Ucys C by immunoturbidimetric assay, determination of SCr. of all the data were analyzed by ELISA. Result The group A 1D RRI, Scys C, Ucys C and SCr and B group were no significant difference, the 2、3d was significantly different; group C 1、2、3d RRI, Scys C, Ucys C and SCr were significantly higher than that in A group and B group D; group 1、2、3d RRI, Scys C, Ucys C and SCr were significantly higher than the other three groups; correlation analysis showed that RRI and Scys C, Ucys C and SCr each time were positively correlated. Conclusion Ultrasonography can effectively reflect the degree of renal damage in sepsis patients complicated with AKI.

关键词

超声

/ 肾动脉阻力指数 / 脓毒症 / 急性肾损伤

Key words

ultrasound

/ renal arterial resident index / metastasizingsepticemia / acute kidney injury

引用本文

EndNote

Ris (Procite)

Bibtex

导出引用

赵　鹏，刘　星，孟祥安，李冰冰，等.

超声测定肾动脉阻力指数在脓毒症合并急性肾损伤患者中的作用

[J]. 湖南师范大学学报医学版. 2018, 15(3): 116-119

Zhao Peng, Liu Xing, Meng Xiang-an,et al.

Role of renal arterial resistance index in patients with sepsis complicated with acute kidney injury

[J]. Journal of Hunan Normal University(Medical Science). 2018, 15(3): 116-119

参考文献

［1］孟启勇, 向镜芬. 免疫功能改变对脓毒症患者预后的影响［J］. 湖南师范大学学报 (医学版), 2013, 10(2): 71-73.

［2］陈建, 张勇. 血必净注射液对脓毒症患者的炎性反应和凝血功能的影响［J］. 湖南师范大学学报 (医学版), 2016, 13(2): 105-107.

［3］赵娜, 田焕, 李志, 等. 脓毒症并发急性肾损伤的危险因素分析与早期诊断［J］. 中华危重病急救医学, 2013, 25(9): 542-545.

［4］邢海波, 吕铁, 盛萍萍, 等. 新型生物标志物对脓毒症急性肾损伤的诊断价值比较［J］. 中国急救医学, 2013, 33(6): 507-510.

［5］张宏民, 刘大为, 王小亭, 等. 感染性休克患者肾血流评分与肾血管阻力指数的关系［J］. 中华医学杂志, 2014, 94(27): 2102-2105.

［6］ Levy MM, Fink MP, Marshall JC, et al.2001 SCCM/ESICM/ACCP/ATS/SIS international Sepsis Definitions Conference［J］. Crit Care Med, 2003, 31(4): 1250-156.

［7］ KhwajaA. KDIGO clinical practice guidelines for acute kidney injury［J］. Nephron ClinPract, 2012, 120(4): c179-c184.

［8］颜伟健, 胡杨青, 卢琳, 等. 急性脑血管疾病并发急性肾损伤相关因素的分析［J］. 湖南师范大学学报 (医学版), 2013, 10(3): 68-70.

［9］ Kellum JA, Lameire N, KDIGO AKI Guideline Work Group. Work Group. Diagnosis, evaluation, and management of acute kidney injury: aKDIGO summary (Part 1) ［J］. Crit Care, 2013, 17(1): 204.

［10］ Zhang Z. Biomarkers, diagnosis and management of sepsis-induced acute kidney injury: a narrative review［J］. Heart Lung Vessel, 2015, 7(1): 64-73.

［11］刘培, 吴京秦, 段美丽. 脓毒症急性肾损伤患者肾功能恢复的影响因素［J］. 山东医药, 2015, 55(41): 16-19.

［12］池锐彬, 邓宇琚, 袁婕, 等. 尿NAG联合血清CysC预测重症患者肾损伤诊断和预后的临床价值急性［J］. 中华急诊医学杂志, 2016, 25(2): 194-199.

［13］何捷, 李达, 严一核, 等. 尿肾损伤分子-1诊断脓毒症急性肾损伤的价值［J］. 实用医学杂志, 2014, 30(1): 87-89.

［14］赵娟, 边毓尧. Scys C和Ucys C在危重患者急性肾损伤时的诊断价值及临床意义［J］. 中国急救医学, 2015, 35(5): 415-417.

［15］李娟, 者星炜, 白云¿. 肾动脉阻力指数在慢性肾脏病人群临床应用现状［J］. 国际泌尿系统杂志, 2014, 34(3): 437-440.