Bibliometric and Visual Analysis of Platelet-Rich Plasma Treatment for Low Back Pain
ZHU Zhichun1, WANG Ge2, XIANG Junhua2, HU Minjuan2, HUANG Weiwei2, TAN Ping2
1. Hunan Provincial Rehabilitation Hospital, Changsha 410021, China; 2. 921st Hospital of the joint service and security force of PLA, Changsha 410003, China
摘要目的：对Web of Science上近10年富血小板血浆（platelet-rich plasma,PRP）治疗下腰痛研究领域的研究进行可视化分析,分析其研究热点及演变趋势,为探索该领域的前沿以及发展方向给出提示。方法：以Web of Science核心集数据库为文献来源,以2012年―2022年间发表的PRP治疗下腰痛相关文献记录为研究对象,检索策略为TS=（platelet rich plasma* OR PRP）and TS=（low back pain* OR LBP）时间跨度=2012年―2022年。利用CiteSpace软件对其进行可视化分析和讨论。结果：2012年―2022年共发表相关文献169篇;文献被引次数最多的是作者Tuakli-Wosornu YA于2016年在PM&R上发表的论文;研究热点集中在间质干细胞、髓核细胞、生长因子等方面,而盘内注射和透明质酸是当前该领域的热点;目前对PRP治疗下腰痛的研究主要集中在椎间盘退行性病变及其结构修复、相关再生医学以及疼痛康复等领域。结论：PRP治疗下腰痛的研究热度不断上升。研究者及机构间还需加强合作,产出高质量研究。研究者目前可对间质干细胞、髓核细胞、生长因子等热点进行研究,而盘内注射和透明质酸可能成为未来研究热点。
Abstract：Objective To visually analyze the research on Platelet-Rich Plasma (PRP) therapy for low back pain in the past 10 years on WoS, analyze its research hotspots and evolutionary trends, provide guidance for exploring the frontier and development direction of this field. Methods The Web of Science Core Collection database was used as the source of literature, and the records of PRP-related literature on low back pain published between 2012 and 2022 were taken as the research object. The search strategy was TS= (platelet rich plasma* OR PRP) and TS= (low back pain* OR LBP) with a time span of 2012-2022. Visual analysis and discussion were conducted using CiteSpace software. Results From 2012 to 2022, 169 related papers were published. The most frequently cited paper was authored by Tuakli-Wosornu YA and published in PM&R in 2016. Research hotspots are concentrated on mesenchymal stem cells, nucleus pulposus cells, growth factors, etc. , while intradiscal injection and hyaluronic acid are currently hot topics within this field. Presently, research on PRP treatment for low back pain is primarily focused on degenerative disc disease and its structural repair, related regenerative medicine and pain rehabilitation. Conclusion The research on PRP treatment for low back pain is continuously increasing in popularity. Cooperation between researchers and institutions needs to be strengthened to produce high-quality research. Currently, researchers can focus on hotspots such as mesenchymal stem cells, nucleus pulposus cells, and growth factors, while intradiscal injection and hyaluronic acid may become future research hotspots.
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2023, Vol. 20 
