Analysis of clinical efficacy of Bushen Lishi Huayu decoction combined with levofloxacin on chronic prostatitis
YANG Shaohua1, TANG Zixi1, TANG Xinjun1, WU Qingling2
1. Department of Traditional Chinese Medicine, Nanxishan Hospital, Guangxi Zhuang Autonomous Region, Guilin 541002, China; 2. Department of Pediatrics, Guilin Integrated Traditional Chinese and Western Medicine Hospital, Guilin 541004, China
Abstract：Objective To explore the clinical efficacy of Bushen Lishi Huayu decoction combined with levofloxacin in the treatment of chronic prostatitis. Methods 80 patients with chronic prostatitis from March 2020 to March 2022 were divided into two group by random number table method. The control group was given levofloxacin treatment, and the observation group was given Bushen Lishi Huayu decoction The clinical efficacy was compared between the two groups. The severity of prostatitis inflammation was evaluated by National Institutes of NIH-CPSI, and the urination function, semen routine indexes, inflammatory factors and immune function indexes were compared. Results The total effective rate of treatment in observation group was higher than that in control group （92.50%vs 75.00%）. The NIH-CPSI score, maximum urine flow rate, average urine flow rate and CD4+/CD8+ in observation group after treatment were higher than those in control group[（10.62±1.91) scores, (21.58±2.92) mL/s, (12.91±0.86) mL/s, (1.52±0.12) vs (14.35±1.74) scores, (19.06±2.30) mL/s, (12.47±0.81) mL/s, (1.39±0.15)], while the levels of interferon-γ (IFN-γ) and tumor necrosis faction-α (TNF-α) in serum and prostatic fluid after treatment were lower than those in control group [ (22.39±4.24) mg/L, (28.31±5.18) mg/L, (95.06±9.31) mg/L and (80.31±8.09) mg/L vs (25.16±3.95) mg/L, (32.59±5.02) mg/L, (110.34±9.85) mg/L and (91.62±8.24) mg/L]. The sperm liquefaction time in observation group after treatment was shorter than that in control group[（27.62±3.41) min vs (29.13±3.06) min]. There were no adverse reactions in both groups during treatment. Conclusion Bushen Lishi Huayu decoction combined with levofloxacin has high effective rate in the treatment of chronic prostatitis. It can relieve the prostatitis symptoms, reduce the levels of body's inflammatory factors, and improve the urination function and immune function.
2023, Vol. 20 
