基于CiteSpace和VOSviewer对微量元素与免疫的文献计量学分析

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Abstract Objective This study aims to employ bibliometric methods for a visual analysis of the intersection between trace elements and immunity. It investigates the research hotspots and development trends in this field and offers a reference for clinical practice and future research. Methods We retrieved publications on micronutrient immunology from the Web of Science Core Collection for the period between January 2000 and December 2022. The bibliometric and visualization analysis was conducted using CiteSpace and VOSviewer. Results Through screening, we identified a total of 1392 relevant publications, with a consistent increase in the publication count over the years, particularly post-2019. China and the Chinese Academy of Sciences emerged as the most productive country and institution, respectively, in this research area. However, their influence was comparatively lower than that of Europe and the United States. Collaboration between authors and institutions from different regions was found to be weak. The journal Biological Trace Element Research exhibited significant activity in this field. Our analysis resulted in the classification of research areas into 9 clusters, including nutritional support, COVID-19, vitamins, selenium, inflammatory bowel disease, liver disease, the elderly, systemic inflammation, and pathogenesis. The research frontiers encompass gut microbiota, inhibition, and human health. Conclusion The results of our bibliometric analysis suggest promising prospects for the development of micronutrient immunology. Current research endeavors focus on the impact of gut microbiota on immune response, the role of trace elements in the immunotherapy of COVID-19, systemic inflammation, and cancer, as well as the influence of dietary nutrition on human health.

Key words： trace elements nutritional immunity bibliometric visual analysis Web of Science

Received: 09 May 2023

PACS:	R151
	G353

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	TANG Leting
	DONG Liping
	ZHAO Mingyi

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TANG Leting,DONG Liping,ZHAO Mingyi. Bibliometric Analysis of Trace Elements and Immunity Based on CiteSpace and VOSviewer[J]. HuNan ShiFan DaXue XueBao(YiXueBan), 2023, 20(4): 102-108.

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http://yxb.hunnu.edu.cn/EN/ OR http://yxb.hunnu.edu.cn/EN/Y2023/V20/I4/102

[1] Gombart A F, Pierre A, Maggini S.A Review of Micronutrients and the Immune System-Working in Harmony to Reduce the Risk of Infection[J]. Nutrients, 2020, 12(1): 236.
[2] Wintergerst E S, Maggini S, Hornig D H.Contribution of selected vitamins and trace elements to immune function[J]. Ann Nutr Metab, 2007, 51(4): 301-323.
[3] Calder P C.Foods to deliver immune-supporting nutrients[J]. Curr Opin Food Sci, 2022, 43: 136-145.
[4] Calder P C, Carr A C, Gombart A F, et al.Optimal Nutritional Status for a Well-Functioning Immune System Is an Important Factor to Protect against Viral Infections[J]. Nutrients, 2020, 12(4): 1181.
[5] 付健, 丁敬达. Citespace和VOSviewer软件的可视化原理比较[J]. 农业图书情报, 2019, 31(10): 31-37.
[6] Liang Y D, Li Y, Zhao J, et al.Study of acupuncture for low back pain in recent 20 years: a bibliometric analysis via CiteSpace[J]. J Pain Res, 2017, 10: 951-964.
[7] Chen D, Zhang G, Wang J, et al.Mapping Trends in Moyamoya Angiopathy Research: A 10-Year Bibliometric and Visualization-Based Analyses of the Web of Science Core Collection (WoSCC)[J]. Front Neurol, 2021, 12: 637310.
[8] Maggini S, Wintergerst E S, Beveridge S, et al. Selected vitamins and trace elements support immune function by strengthening epithelial barriers and cellular and humoral immune responses [J]. Br J Nutr, 2007, 98 Suppl 1: S29-35.
[9] Shankar A H, Prasad A S.Zinc and immune function: the biological basis of altered resistance to infection[J]. Am J Clin Nutr, 1998, 68(2 Suppl): 447s-463s.
[10] Michaudel C, Sokol H.The Gut Microbiota at the Service of Immunometabolism[J]. Cell Metab, 2020, 32(4): 514-523.
[11] Limketkai B N, Hamideh M, Shah R, et al.Dietary Patterns and Their Association With Symptoms Activity in Inflammatory Bowel Diseases[J]. Inflamm Bowel Dis, 2022, 28(11): 1627-1636.
[12] Huang L J, Mao X T, Li Y Y, et al. Multiomics analyses reveal a critical role of selenium in controlling T cell differentiation in Crohn's disease [J]. Immunity, 2021, 54(8): 1728-1744. e7.
[13] Bermano G, Méplan C, Mercer D K, et al.Selenium and viral infection: are there lessons for COVID-19?[J]. Br J Nutr, 2021, 125(6): 618-627.
[14] Kieliszek M, Lipinski B.Selenium supplementation in the prevention of coronavirus infections (COVID-19)[J]. Med Hypotheses, 2020, 143: 109878.
[15] Heller R A, Sun Q, Hackler J, et al.Prediction of survival odds in COVID-19 by zinc, age and selenoprotein P as composite biomarker[J]. Redox Biol, 2021, 38: 101764.
[16] Karam G, Agarwal A, Sadeghirad B, et al.Comparison of seven popular structured dietary programmes and risk of mortality and major cardiovascular events in patients at increased cardiovascular risk: systematic review and network meta-analysis[J]. Bmj, 2023, 380: e072003.
[17] Thielmann C M, Costa da Silva M, Muley T, et al. Iron accumulation in tumor-associated macrophages marks an improved overall survival in patients with lung adenocarcinoma[J]. Sci Rep, 2019, 9(1): 11326.
[18] Lv M, Chen M, Zhang R, et al.Manganese is critical for antitumor immune responses via cGAS-STING and improves the efficacy of clinical immunotherapy[J]. Cell Res, 2020, 30(11): 966-979.
[19] Wang C, Guan Y, Lv M, et al. Manganese Increases the Sensitivity of the cGAS-STING Pathway for Double-Stranded DNA and Is Required for the Host Defense against DNA Viruses [J]. Immunity, 2018, 48(4): 675-687. e7.