单侧全聋型突聋患者临床特征和血液学参数与预后的相关性研究

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Abstract Objective To investigate the clinical characteristics and laboratory test results (such as hematological parameters) of patients with sudden unilateral total sensorineural hearing loss and to explore the factors affecting the curative effect of hearing recovery. Methods The clinical and laboratory examination data of 89 patients with sudden unilateral total sensorineural hearing loss hospitalized in Changsha Fourth Hospital Affiliated to Hunan Normal University from September 2019 to October 2022 were collected, and the gender, age, affected ears, time from onset to medical treatment, accompanied symptoms (tinnitus, dizziness, ear tightness), accompanied diseases (hypertension, diabetes, heart disease, hyperlipidemia) and the influence of hematological parameters (neutrophil number, lymphocyte number, fibrinogen, albumin, blood lipid) on prognosis. Results Univariate analysis showed that the time from onset to treatment, gender, affected ear, tinnitus, ear fullness, hypertension, diabetes, heart disease and hyperlipidemia were not related to the efficacy of patients with unilateral total sudden deafness. The effective rate of patients over 40 years old was 33.90%, which was significantly lower than 86.96% of patients under 40 years old. The effective rate of patients with vertigo was 25%, which was lower than 63.4% of patients without vertigo. Neutrophil count, lymphocyte count, platelet count, fibrinogen, albumin, triglyceride, low-density lipoprotein, FAR, PLR, NLR were not related to the prognosis of patients with unilateral total sudden deafness. There was a significant correlation between total cholesterol and high-density lipoprotein. Multivariate Logistic regression analysis of age, vertigo, total cholesterol and high-density lipoprotein showed that age was not related to the prognosis of patients with unilateral sudden deafness, while vertigo, total cholesterol and high-density lipoprotein were significantly related. Conclusion vertigo, total cholesterol and high-density lipoprotein are important risk factors for auditory recovery in patients with sudden unilateral total deafness.

Key words： sudden hearing loss total deafness hematological parameters clinical symptoms prognosis

Received: 28 November 2022

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	SHI Ying
	DENG Xiaowen
	SONG Guilin

Cite this article:

SHI Ying,DENG Xiaowen,SONG Guilin. Correlation between clinical characteristics, hematological parameters and prognosis in patients with sudden unilateral total sensorineural hearing loss[J]. HuNan ShiFan DaXue XueBao(YiXueBan), 2023, 20(1): 97-100.

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http://yxb.hunnu.edu.cn/EN/ OR http://yxb.hunnu.edu.cn/EN/Y2023/V20/I1/97

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