Objective To analyze the risk factors of deep venous thrombosis in patients undergone hip replacement, and to investigate the application value of Autar Scale risk assessment. Methods A total of 101 cases of patients admitted to hospital from January 2015 to December 2016 and undergone hip replacement were selected as the research objects. The methods of single factor and multi-factor logistic regression analysis were used to analyze the risk factors of deep venous thrombosis in those patients, and Autar Scale was used to assess the risk degree of deep venous thrombosis. Results Among the 101 cases of patients, 15 cases had postoperative deep venous thrombosis, with the incidence rate of 14.85%. Single factor analysis showed that the incidence rate of deep venous thrombosis in female patients and patients with complicating diseases (hypertension, diabetes, cardiovascular and cerebrovascular diseases) was significantly higher than that of patients without deep venous thrombosis; the incidence rate of patients with postoperative early activities and postoperative use of anticoagulants was significantly lower than that of patients without deep venous thrombosis; the incidence rate of aged patients was significantly higher than that of patients without deep venous thrombosis. Multi-factor logistic regression analysis showed that female, advanced age, complicated hypertension, diabetes and cardiovascular and cerebrovascular disease are risk factors of deep venous thrombosis after hip replacement, postoperative early activities and postoperative use of anticoagulants are protective factors that prevent deep venous thrombosis; the incidence rate of deep venous thrombosis in high risk patients was significantly higher than that of low risk and medium risk patients; the incidence rate of deep venous thrombosis in medium risk patients was significantly higher than that in low risk patients. Conclusion The incidence rate of deep venous thrombosis in patients undergone hip replacement is high, and it is significantly correlated with gender, age and complicating diseases. The risk assessment on deep venous thrombosis should be strengthened, and predictable and targeted nursing intervention strategies should be proposed to reduce the incidence rate of deep venous thrombosis.