补肾利湿化瘀汤联合左氧氟沙星治疗慢性前列腺炎的临床疗效分析

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Abstract Objective To explore the clinical efficacy of Bushen Lishi Huayu decoction combined with levofloxacin in the treatment of chronic prostatitis. Methods 80 patients with chronic prostatitis from March 2020 to March 2022 were divided into two group by random number table method. The control group was given levofloxacin treatment, and the observation group was given Bushen Lishi Huayu decoction The clinical efficacy was compared between the two groups. The severity of prostatitis inflammation was evaluated by National Institutes of NIH-CPSI, and the urination function, semen routine indexes, inflammatory factors and immune function indexes were compared. Results The total effective rate of treatment in observation group was higher than that in control group （92.50%vs 75.00%）. The NIH-CPSI score, maximum urine flow rate, average urine flow rate and CD4⁺/CD8⁺ in observation group after treatment were higher than those in control group[（10.62±1.91) scores, (21.58±2.92) mL/s, (12.91±0.86) mL/s, (1.52±0.12) vs (14.35±1.74) scores, (19.06±2.30) mL/s, (12.47±0.81) mL/s, (1.39±0.15)], while the levels of interferon-γ (IFN-γ) and tumor necrosis faction-α (TNF-α) in serum and prostatic fluid after treatment were lower than those in control group [ (22.39±4.24) mg/L, (28.31±5.18) mg/L, (95.06±9.31) mg/L and (80.31±8.09) mg/L vs (25.16±3.95) mg/L, (32.59±5.02) mg/L, (110.34±9.85) mg/L and (91.62±8.24) mg/L]. The sperm liquefaction time in observation group after treatment was shorter than that in control group[（27.62±3.41) min vs (29.13±3.06) min]. There were no adverse reactions in both groups during treatment. Conclusion Bushen Lishi Huayu decoction combined with levofloxacin has high effective rate in the treatment of chronic prostatitis. It can relieve the prostatitis symptoms, reduce the levels of body's inflammatory factors, and improve the urination function and immune function.

Key words： bushen lishi huayu decoction levofloxacin combined therapy chronic prostatitis clinical efficacy

Received: 18 April 2023

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R255.5

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	YANG Shaohua
	TANG Zixi
	TANG Xinjun
	WU Qingling

Cite this article:

YANG Shaohua,TANG Zixi,TANG Xinjun等. Analysis of clinical efficacy of Bushen Lishi Huayu decoction combined with levofloxacin on chronic prostatitis[J]. HuNan ShiFan DaXue XueBao(YiXueBan), 2023, 20(3): 140-142.

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http://yxb.hunnu.edu.cn/EN/ OR http://yxb.hunnu.edu.cn/EN/Y2023/V20/I3/140

[1] 刁建军, 吴波, 张姝红, 等. 慢性前列腺炎患者前列腺液中WBC, SPL, Ig及趋化因子水平变化及意义[J]. 重庆医学, 2022, 51(10) : 1665-1669.
[2] 王志勇, 崔伟锋, 李星锐, 等. 夏荔芪胶囊联合左氧氟沙星治疗IIIA型慢性前列腺炎的疗效观察[J]. 现代药物与临床, 2020, 35(12) : 2391-2395.
[3] 刘明阳, 毕焕洲, 陈启光. 中药塌渍联合左氧氟沙星, 坦索罗辛治疗慢性前列腺炎的临床疗效分析[J]. 实用药物与临床, 2021, 24(4) : 345-348.
[4] 张华, 陈建设, 孙自学, 等. 守仙五子丸加减联合督灸治疗慢性前列腺炎肾虚血瘀证的疗效观察[J]. 时珍国医国药, 2022, 33(6) : 1394-1396.
[5] 中国中医药信息学会男科分会. 慢性前列腺炎中西医结合多学科诊疗指南[J]. 中华男科学杂志, 2020, 26(4) : 369-376.
[6] 中国中医药信息学会男科分会. 慢性前列腺炎中西医结合诊疗指南 (试行版)[J]. 中国中西医结合杂志, 2007, 27(11) : 1052-1056.
[7] 洪锴, 许清泉, 姜辉, 等. 慢性前列腺炎症状评分表临床应用及分析[J]. 中华男科学, 2002, 8(1) : 38-41.
[8] 秦远, 宋宁宏, 叶和松, 等. 淋舒汤联合左氧氟沙星治疗以下尿路症状为主的ⅢA型前列腺炎湿热下注证的疗效观察[J]. 中华男科学杂志, 2020, 26(11) : 1025-1029.
[9] 孙自学, 张珈铭, 陈建设, 等. 益肾通络方治疗Ⅲ型前列腺炎肾虚络阻型患者的疗效评价[J]. 中国中西医结合杂志, 2020, 40(11) : 65-69.
[10] 田超, 李晓阳, 靳继宏, 等. 他达拉非降阶梯治疗联合补肾利湿化瘀汤对Ⅲ型前列腺炎合并勃起功能障碍的疗效[J]. 医学临床研究, 2021, 38(9) : 1434-1436.
[11] 李久现, 张晓丹, 冯帅英, 等. 补肾利湿活血汤治疗特发性少弱精子症[J]. 中医学报, 2019, 34(4) : 847-851.
[12] 杨超, 闫庆梓, 唐洁, 等. 蒲公英挥发油成分分析及其抗炎抗肿瘤活性研究[J]. 中华中医药杂志, 2018, 33(7) : 3106-3111.
[13] 周世英, 何书明, 陈宁. 双石通淋胶囊联合坦索罗辛治疗ⅢB型前列腺炎伴精液不液化的临床观察[J]. 中国性科学, 2021, 30(8) : 28-31.
[14] 朱勇, 葛晓东, 施勇, 等. 前列腺炎Ⅰ号治疗慢性前列腺炎合并精液不液化的临床疗效评价[J]. 中医药导报, 2020, 26(15) : 91-93.
[15] 罗克燕, 杨丹莉, 徐敏. 菟丝子总黄酮对排卵障碍大鼠下丘脑-垂体-卵巢轴性激素水平的影响[J]. 中国实验方剂学杂志, 2013, 19(13) : 258-260.
[16] 苏洁, 陈素红, 吕圭源, 等. 杜仲及菟丝子对肾阳虚大鼠生殖力及性激素的影响[J]. 浙江中医药大学学报, 2014, 38(9) : 1087-1090.
[17] 张堃, 吕向坤, 焦艾丽, 等. 菟丝子总黄酮对先兆流产大鼠妊娠结局及Th1/Th2平衡的作用机制研究[J]. 现代中药研究与实践, 2022, 36(4) : 24-28.
[18] 石和元, 桑红灵, 谭爱华, 等. 山茱萸多糖对免疫抑制小鼠免疫功能的影响[J]. 现代免疫学, 2022, 42(6) : 482-488.