二术合剂穴位贴敷、拔罐联合足浴方对小儿胃肠功能紊乱症状改善及免疫功能、炎症状态的影响

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Abstract Objective To observe the effects of erzhu heji acupoint sticking,cupping combined with foot bath prescription on the improvement of symptoms,immune function and inflammatory state of gastrointestinal dysfunction（spleen deficiency syndrome）in children. Methods This is a prospective study.A total of 124 children with diarrhea symptoms of gastrointestinal dysfunction were selected as research objects and randomly divided into control group and observation group,with 62 cases in each group. Control group was given live clostridium caseinate powder orally,when necessary,given antivomiting,rehydration and other conventional treatment;Observation group was treated with Erzhu mixture acupoint application,cupping and foot bath for 7 days. The therapeutic effect and gastrointestinal symptom grading score（GSRS）of the two groups were compared,the improvement of stool character and frequency was observed,and the changes of immune function related indexes（IgG,IgA,IgM,zinc）and inflammatory status indexes（TNF-α,CRP,IL-17）were monitored. Results The effective rates of control group and observation group were 88.71% and 96.77%,respectively,with no statistical significance. However,the rank sum test according to different treatment levels showed that the clinical efficacy of the observation group was better,and the difference was statistically significant. The scores of abdominal distension,abdominal pain,nausea and vomiting in observation group were significantly lower than those in control group. In the observation group,the characteristics of stool were significantly improved from day 3,and tended to be formed gradually. In addition,the improvement of stool traits in the observation group was more obvious,and the score of stool traits was significantly lower than that in the control group. After treatment,the frequency of stool was reduced,and the frequency of stool was significantly reduced from the 2nd day. The number of stool in the observation group was significantly less than that in the control group at the same time point. Compared with before treatment,after treatment,the body immunity was increased,the inflammatory state was alleviated,the levels of immunoglobulin IgG,IgA,IgM and zinc contents were significantly increased,and the serum levels of TNF-α,CRP,IL-17 were significantly decreased. The changes of each index in the observation group were more obvious than those in the control group. Conclusion The curative effect of the combination of acupoint application and cupping combined with foot bath prescription in the treatment of gastrointestinal dysfunction in children is definite,which is beneficial to improve the symptoms,and may be related to correcting the disorder of immune function and alleviating the body's inflammatory response.

Key words： children gastrointestinal dysfunction acupoint application clostridium caseinate live powder symptom improvement immune function inflammatory state

Received: 28 February 2023

PACS:

R725.7

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	YU Xiaoli
	ZHU Lihui
	HUANG Fengmei

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YU Xiaoli,ZHU Lihui,HUANG Fengmei. Effect of the combination of Erzhuheji acupoint sticking,cupping combined with foot bath on the improvement of symptoms,immune function and inflammatory state of gastrointestinal dysfunction（spleen deficiency syndrome）in children[J]. HuNan ShiFan DaXue XueBao(YiXueBan), 2023, 20(2): 79-83.

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http://yxb.hunnu.edu.cn/EN/ OR http://yxb.hunnu.edu.cn/EN/Y2023/V20/I2/79

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