Abstract：Objective To analyze the pathogens, drug resistance and risk factors of puerperal infection. Methods The clinical data of 124 parturients who delivered in our hospital from July 2020 to December 2021 were analyzed retrospectively. The infection rate, pathogenic bacteria and drug resistance were counted, and the risk factors of infection were analyzed. Results The infection rate was 7.26% in 9 parturients. The main infection sites were perineum incision (33.33%) and genital tract (22.22%). A total of 36 pathogens were detected, including 19 gram-negative bacteria (52.78%), 14 gram-positive bacteria (38.89%) and 3 fungi (8.33%). The resistance rate of gram-negative bacteria (Escherichia coli, Pseudomonas aeruginosa) to rifampicin, vancomycin and meropenem was low. Gram-positive bacteria (Staphylococcus aureus, Enterococcus faecalis) had low resistance rates to vancomycin and imipenem. Multivariate logistic regression analysis showed that pregnancy complications, prenatal anemia, postpartum hemorrhage, labor process time ≥ 8 h, rupture time ≥ 12 h, and soft birth canal injury were independent risk factors of puerperal infection. Conclusion Gram-negative bacteria and positive bacteria were the main pathogens of puerperal infection, and the antibiotics with high sensitivity should be selected according to the drug resistance. There are many factors influencing puerperal infection, and corresponding preventive measures can be taken according to relevant risk factors.
2023, Vol. 20 
