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| The relationship between chronic renal insufficiency and pulmonary artery pressure and its related factors |
| YUAN Yuan, WANG Qianyun, LIU Chunhui, YANG Hairong, WANG Xiangchuan |
| Department of Nephrology, Second Affiliated Hospital of Hunan Normal University/Department of Nephrology, 921st Hospital of the joint service and security force of the Chinese People's Liberation Army, Changsha 410003, China |
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Abstract Objective To investigate the relationship between glomerular filtration rate and pulmonary artery pressure, and to analyze the risk factors for CKD progression. Methods The patients with CKD who visited the 921st Hospital of the Joint Logistics Support Force between January 2019 and December 2021 were retrospectively analyzed, and the variation characteristics of pulmonary artery pressure under different glomerular filtration rate (eGFR) were analyzed, and the effects of various factors on patients with chronic renal insufficiency were compared. Results As the CKD staging increased, the pulmonary artery pressure showed a gradual increase trend. Among the 119 patients with CKD, there were 18 cases with combined pulmonary hypertension, 0 cases including 1-2 stage, 4 cases in stage 3, 6 cases in stage 4, and 8 cases in stage 5. At the same time, with the decrease of eGFR (glomerular filtration rates), the patient's hemoglobin (Hb) and platelet (PLT) decreased, and the D2 polymer increased. Conclusion There is an inverse relationship between pulmonary artery pressure and eGFR, that is, when eGFR decreases, cardiovascular risk increases, and early CKD patients actively treat anemia, reducing pulmonary artery pressure can aueviate the progression of kidney disease.
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Received: 14 March 2023
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2023, Vol. 20 
