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Status of blood lipids in elderly patients with coronary heart disease and the influence of secondary prophylactic medication on blood lipid levels |
ZHANG Xiaobo, RONG Guoling |
Department of Geriatrics, Dazhou Central Hospital, Dazhou 635000, China |
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Abstract Objective To investigate the status of blood lipids and secondary prophylactic medication in elderly patients with coronary heart disease, and analyze the influence of secondary prophylactic medication on blood lipid control. Methods An epidemiological cross-sectional study from January 2020 to March 2023 was conducted. The general information, blood lipids and secondary prophylactic medication of elderly patients with coronary heart disease admitted to the hospital were investigated to identify the factors affecting blood lipid control of elderly patients with coronary heart disease. Results A total of 536 elderly patients with coronary heart disease were enrolled, including 265(49.44%) patients with hypercholesterolemia, 207(38.62%) patients with hypertriglyceridemia, 274(51.12%) patients with mixed hyperlipidemia, 198(36.94%) patients with low HDL-C, 354(66.04%) patients with inadequately controlled blood lipids, and 182(33.96%) patients with standard blood lipid control. The proportions of patients treated with antiplatelet drugs, β-blockers, lipid-lowering drugs, and ACEI/ARB drugs were 58.40%, 51.49%, 29.29%, and 49.63%. There were significant differences between the inadequately controlled blood lipids group and the standard blood lipid control group in terms of the course of coronary heart disease, diabetes history, the usage rate of lipid-lowering statins, compliance with secondary prophylactic medication, and duration of secondary prophylactic medication. The course of coronary heart disease ≥5 years, diabetes history, no use of lipid-lowering drugs and poor compliance with secondary prophylactic medication were independent risk factors for blood lipid control failure in elderly patients with coronary heart disease. The variance inflation factor (VIF) was under 3. Conclusion Blood lipid abnormalities are common in elderly patients with coronary heart disease, and the status of blood lipid control is not optimistic. Reasonable secondary prophylactic medication, especially standard use of lipid-lowering statins, can lower blood lipid levels in elderly patients with coronary heart disease, which is conducive to obtaining standard blood lipids.
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Received: 30 March 2023
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