联动成像模式对结直肠小型无蒂锯齿状病变的诊断价值

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摘要 目的: 本研究旨在研究联动成像（linked color imaging,LCI）对比窄带成像（narrow-band imaging,NBI）在结直肠微小锯齿状病变诊断中的价值。方法: 本项目为前瞻性研究。选取2024年1月―7月在皖南医学院第二附属医院接受结肠镜检查的664例患者,随机分为LCI组和NBI组。比较两组在结直肠微小息肉数量的检出率、肠道各部位息肉检出率,息肉不同山田分型检出率并进行相应病理诊断结果对比。结果: LCI组微小息肉的总检出率高于NBI组,右半结肠微小息肉检出率LCI组高于NBI组;尤其在山田Ⅰ型病变的检出率上,LCI组显著高于NBI组。病理学结果方面,LCI组检出的炎性息肉和无蒂锯齿状病变数量均高于NBI组。结论: LCI技术在提高结直肠微小息肉,尤其是右半结肠微小息肉和无蒂锯齿状病变的检出率方面具有显著优势,对预防结直肠癌的发生具有重要的临床意义。

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	金雷
	李纯双
	陈丽萍
	陈传荣

关键词 ：联动成像, 窄带成像, 结肠镜, 微小息肉, 无蒂锯齿状病变

Abstract： Objective This study aims to investigate the value of link color imaging (LCI) compared with Narrow Band Imaging (NBI) in the diagnosis of minute serrated lesions in the colon and rectum. Methods A prospective study was conducted from January to July 2024, including 664 patients who underwent colonoscopy at the Second Affiliated Hospital of Wannan Medical College. Patients were randomly divided into the LCI group and the NBI group. The study compared the detection rates of minute polyps in the colon and rectum, the detection rates of polyps in different parts of the intestine, the detection rates of different Sanada typing of polyps, and the corresponding pathological comparison between the two groups. Results The overall detection rate of minute polyps in the LCI group was higher than that in the NBI group (P<0.05), and the detection rate of minute polyps in the right hemicolon was higher in the LCI group than in the NBI group; especially in the detection rate of Sanada type I lesions, the LCI group was significantly higher than the NBI group (P<0.001). In terms of pathological results, the number of inflammatory polyps and sessile serrated lesions detected in the LCI group was higher than that in the NBI group (P<0.05). Conclusion LCI technology has a significant advantage in improving the detection rate of minute polyps in the colon and rectum, especially minute polyps in the right half of the colon and sessile serrated lesions, which has important clinical significance for the prevention of colorectal cancer.

Key words： link color imaging narrow band imaging colonoscopy small polyps sessile serrated adenomas

收稿日期: 2024-07-10

中图分类号:

R574.62

基金资助:国家自然科学基金面上项目“多部分级靶向诱饵外泌体递释系统瘤内级联免疫激活克服三阴性乳腺癌耐药的研究”（82373294）;芜湖市科技局课题项目“SMYD2通过组蛋白甲基化修饰激活EVI2A表达促进免疫逃逸诱导胰腺癌化疗耐药的机制研究”（2023jc24）;芜湖市卫健委科研项目“PDK4抑制铁死亡诱导胰腺癌吉西他滨耐药的机制研究”（WHWJ2023y013）

通讯作者: 陈传荣,E-mail：crchen1227@163.com

引用本文:

金雷, 李纯双, 陈丽萍, 陈传荣. 联动成像模式对结直肠小型无蒂锯齿状病变的诊断价值[J]. 湖南师范大学学报(医学版), 2024, 21(5): 107-110. JIN Lei, LI Chunshuang, CHEN Liping, CHEN Chuanrong. The diagnostic value of linkage imaging mode for small sessile serrated lesions in the colon. HuNan ShiFan DaXue XueBao(YiXueBan), 2024, 21(5): 107-110.

链接本文:

http://yxb.hunnu.edu.cn/CN/ 或 http://yxb.hunnu.edu.cn/CN/Y2024/V21/I5/107

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