Research progress on the application of antimicrobial peptides in the detection of foodborne pathogenic bacteria
LI Xiang1,2,3,4, ZHENG Xi1,2,3,4, GUO Yulan5, XU Kun1,2,3,4
1. School of Medicine, Hunan Normal University, Changsha 410013; 2. Key Laboratory of Model Animals and Stem Cell Biology in Hunan Province, Changsha 410013; 3. Engineering Research Center of Reproduction and Translational Medicine of Hunan Province, Changsha, 410013; 4. Key Laboratory of Molecular Epidemiology of Hunan Province, Changsha 410013; 5. Jilin University, Changchun 130000
Abstract：Foodborne diseases caused by pathogenic bacteria are a serious threat to human health and a serious public health problem. Rapid and accurate detection of foodborne pathogenic bacteria in food is important for the prevention and control of foodborne diseases. In recent years, a variety of different highly sensitive and specific rapid detection methods have been developed with the aim of realizing the rapid detection of pathogenic bacteria in food. These methods all need to specifically identify bacteria from complex food matrixes. To achieve this goal, many small molecule substances have been developed, such as antibodies, aptamers, phages, antimicrobial peptides (AMPs), lectins, and enzymes. These small molecule substances have different advantages and disadvantages in application. The application of antimicrobial peptides has received more and more attention because of their high stability, simple synthesis, easy availability, high affinity for bacteria, low cost of AMPs compared with antibodies, DNA probes, more stable in harsh environments, and easy to be mass-produced. Therefore, they are being applied to the development and utilization of a variety of rapid detection methods. In this review, we systematically summarized the application of antimicrobial peptides in the detection of foodborne pathogens, and discussed its application prospects.
李湘, 郑希, 郭玉兰, 徐坤. 抗菌肽在食源性致病菌检测中的研究进展[J]. 湖南师范大学学报(医学版), 2023, 20(6): 1-8.
LI Xiang, ZHENG Xi, GUO Yulan, XU Kun. Research progress on the application of antimicrobial peptides in the detection of foodborne pathogenic bacteria. HuNan ShiFan DaXue XueBao(YiXueBan), 2023, 20(6): 1-8.
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