Abstract:Objective To investigate the clinical effects of left hepatectomy with hepatolithiasis guided by liver fibrosis border and anatomical left hepatectomy with hepatolithiasis guided by the ischemic line. Methods Forty-five patients with hepatobiliary lithiasis in Hunan Provincial People's Hospital from June 2018 to September 2020 were retrospectively analyzed.23 cases in the experimental group and 22 cases in the conventional group. The patients in both groups were compared with thetotal bilirubin (TBIL), alanine aminotransferase (ALT), aspartate aminotransferase (AST) and albumin (ALB) on the last 1 day before operation, on the 1st day and the 5th day after operation. operation time, intraoperative bleeding, Middle hepatic vein exposure, postoperative ambulation, postoperative intestinal function recovery time, postoperative eating time, postoperative hospital days and postoperative pain and other indicators on the last 1 day before operation, on the 1st day and the 5th day after operation. Results The two groups of patients were successfully completed surgery, postoperative recovery were good. T-tube Cholangiography confirmed the absence of residual stones after 2 months later. Comparing with thetotal bilirubin (TBIL), alanine aminotransferase (ALT), aspartate aminotransferase (AST) and albumin (ALB) on the last 1 day before operation, on the 1st day and the 5th day after operation, there is no significant difference between the two group. In the operation time, intraoperative bleeding, the data suggest that there is statistical differences between the two groups. There is no significant difference with the Middle hepatic vein exposure between the two groups. The postoperative ambulation, postoperative intestinal function recovery time, postoperative eating time, postoperative hospital stay, Postoperative pain and other aspects of the two groups showed no significant difference. Conclusion The left hepatectomy with hepatolithiasis guided by liver fibrosis border based on the hepatic blood flow control technique of anatomical hepatectomy, relative to the characteristics of hepatolithiasis lesions, has a better clinical value in the left hepatectomy with significant hepatic atrophy and fibrosis in hepatolithiasis .