Observation on the therapeutic effect of isotretinoin capsules combined with ozone hydrotherapy method on acne
CHEN Ling1, HU Weicai2, CHEN Weifeng2, HUANG Ling2, DENG Chunlei3
1. Department of Dermatology, The Third Hospital of Changsha, Changsha 410005, China; 2. Department of Dermatology, Yiyang Central Hospital, Yiyang 413000, Chuna; 3. School of Medicine, Hunan Normal University, Changsha 410013, China
Abstract：Objective To observe the clinical effect of isotretinoic acid combined with ozone hydrotherapy on acne vulgaris. Methods 112 patients with acne vulgaris were retrospectively analyzed and divided into observation group (56 cases) and control group (56 cases). The patients in the control group received oral intervention with isotretinoic acid capsules, while the patients in the observation group received ozone hydrotherapy intervention on the basis of isotretinoic acid capsules, and the clinical effects of the two groups were observed. Results The total effective rate of patients in the observation group was 92.86%, significantly higher than 73.21% in the control group. The regression rate of white head acne, black head acne, sebum overflow, papules and pustules in the observation group was significantly higher than that in the control group. There was no significant difference in the incidence of adverse reactions between the two groups. Conclusion Isoretinoic acid combined with ozone hydrotherapy can significantly improve the efficacy of acne vulgaris and promote the regression of skin lesions, which is suitable for clinical application.
2023, Vol. 20 
